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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,303 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10303)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Erin C.
Coram, NY
113 reviews
Beauty Junkie Expert Level 3
Decent spot treatment. Use after you pop a zit right before you sleep and run it in. When you wake up it will dry it out and the redness will be non existent.
Sheena D.
Wichita, KS
101 reviews
I use this all the time! I love how you can put it on just the spots that need treating. It works great to stop acne and get my face back clean and acne free.
Kaitlyn H.
Youngstown, OH
22 reviews
Beauty Junkie Expert Level 3
This works great! Doesn't remove the pimple completely but reduces it in size over night! It kind of stings, but it works. Rubbing Alcohol works just as well.
Rebeca S.
12 reviews
Really helps reduce redness when you already have a pimple and to prevent more. Unfortunately, I had to stop using it because it gave me an allergic reaction.
Eve W.
18 reviews
I use this product in the morning for acne that I want to hide or treat. The best thing about this product is that it is clear and you can put makeup over it!
Emma M.
Madison, WI
135 reviews
Beauty Junkie Expert Level 2
This is great! It takes care of spots I have pretty quickly, and brings redness down. I like that it's pretty inexpensive and easily found yet it's effective!
Raven G.
Palm Coast, FL
48 reviews
a great product at a good price. i get mine from target. they are soft clothes and you don't have to be afraid to you it on your eyes because its really gentle
Karlie B.
Alpine, UT
104 reviews
Beauty Junkie Expert Level 2
I don’t know if this was a placebo effect or what but I do feel like it helped to diminish the look of my pimple, make it less red and help it disappear faster
Amber A.
mount pleasant pa
47 reviews
Beauty Junkie Expert Level 1
I had high hopes for this. Unfortunately it didn't meet my expectations. I didn't really notice a difference in my skin at all even after a couple weeks of use
Sienna M.
State College, PA
75 reviews
Beauty Junkie Expert Level 4
This product is fantastic! It quickly reduces pimples and is great prevention when used on forming bumps. It did not dry out my skin like other products have.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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