Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,507 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10507)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Brianna N.
79 reviews
Beauty Junkie Expert Level 1
This product works wonders when in comes to acne but recently I discovered that equate is very similar and for the price I would rather go with the cheaper one.
juno b.
55 reviews
I'd say it's good for the price and amount given . It works it used on a daily basis . I had a bit of redness after use and burning and itching while I applied.
Jackie L.
Anaheim, CA
115 reviews
Beauty Junkie Expert Level 2
The only good thing about this product is that it made the swelling go down on the random pimples I got but it didn't make the pimples disappear like it claims.
Cassie R.
36 reviews
Beauty Junkie Expert Level 4
This product is excellent! It works very well on spots, it dries them up overnight! I wouldn't recommend using this product every day because it can be drying.
Lacy M.
Madera, CA
143 reviews
Beauty Junkie Expert Level 4
I love this stuff. It only takes a tiny bit dabbed on a problem area and it seems to be cleared up within a day or so, depending on how bad the problem area is.
Kailyn M.
64 reviews
Beauty Junkie Expert Level 1
Purchased at: Walmart
Effective. Harsh in smell and can cause skin the dry out a little, but absolutely does its job! Pricey for such a small tube, but it gets my thumbs up for sure!
Fatima J.
Morton Grove, IL
32 reviews
It’s only meh. It smells good. But it’s a little overpriced at a price of 7 dollars. I like the clean and clear moisturizer for acne. It’s lightweight and nice.
Kristina P.
104 reviews
Beauty Junkie Expert Level 2
I wouldnt re buy it forst time user burned my face my face turned red if u have sensitive skin recommend do not use disappointing i really thought it would work
Kachira C.
Mount Union, PA
240 reviews
I haven't used this product in a while. When I did though i believed that it worked well. The only reason i switched was because my face was getting used to it.
Katelynn M.
Grand Terrace, CA
131 reviews
Beauty Junkie Expert Level 2
Great product. I've used it for years and I truly think it's an amazing product. Pretty pricey for the tiny amount that you get but it definitely works wonders.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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