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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,294 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10294)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Sandra R.
Forest Park, GA
44 reviews
Beauty Junkie Expert Level 3
It does work... But I wouldn't give it 5 stars... I truly think there are better. But it does help so I would give a try if your looking for something different.
Ann M.
Spring, TX
12 reviews
I don't have any big pimple/acne problems but Whenever i get a bad breakout it works AMAZINGLY!! I do have some very small blemishes that go away as easily but a WONDERFUL product!!
Abbie M.
Redmond, WA
3 reviews
I love this product so so so so much. It is a full on life saver. I apply it at night to any acne spots I have and 97% of the time they are gone by the morning. I adore this product
Amity M.
Buffalo, NY
8 reviews
Works great for young people with mild acne. As I got older my skin changed and so did my skincare needs. Wasn't the best product for me anymore but def. recommend for under 25
Joanna A.
42 reviews
My husband and I religiously use the spot treatment anytime we need. We dab a little onto trouble spots right before bed and we're always pleased in the morning!
Julie N.
Vallejo, CA
70 reviews
I had really bad acne at one point, and this just gave me really dry skin to cause me to break out more. I'm giving this a C because i believe that this just wasn't for my skin.
Hannah K.
Ft. Carson, CO
2 reviews
I love this stuff! It works so quickly and keeps those annoying zits gone! It has a slight burn in the beginning but nothing you can't handle. This is the best stuff I've used!
Diana M.
Miami, FL
38 reviews
This works!

I have had random zits show up on obviously places and this product has saved my life within minutes!

This is definitely something you want to carry in your purse
Rayah M.
New City, NY
28 reviews
I love this! It clears up my acne over night! It doesn't dry out my skin and i have really dry skin! My brother uses too and he loves it! I would repurchase it again and again!
Vanessa N.
De Queen, AR
63 reviews
Its been some years ago that ive tried this. bit i used it to get the pop ups over night. it works the last time i used it. but since them ive had no real need for it now :)
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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