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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,303 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10303)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Alexandra C.
Winter Park , FL
299 reviews
Beauty Junkie Expert Level 5
This stuff is a great preventative product. If I start to see a blemish begin I start applying this. It is not as strong at getting rid of an already existing blemish.
Kristen H.
Cusseta, GA
7 reviews
Ive used this product fir many years & it works great. use it on pimples before they get out of control & on ones that are already inflamed. i use the whole clean & clear line for best results.
Jessica D.
Porter Ranch, CA
16 reviews
I use this product when I have really bad break outs. In about 2 days it isn't completely gone but the redness has gone away and the breakout is much smaller than it originally was. This has been staple product for me for years.
Ebony W.
Cambria Heights , New York
13 reviews
I was breaking out before a pageant and i was so heartbroken. but this product saved me. the applicator is precise and sanitary.this product works fast, and it is affordable!

PS. I WON! :)
Sarah B.
62 reviews
When I have a bad break out I always reach for this stuff. It works well. Normally getting rid of a pimple in 24-48 hours. I wish the tube was bigger but it works well.
Mandy H.
Brooklyn, NY
11 reviews
It didn't really do much for my acne at all. On top of that my face would sting when I put it on top of any kind of previous/open acne wounds. Definitely not enjoyable.
Rebeca I.
149 reviews
This is a pretty good spot treatment, dries out the blemish really fast (like in 2 days if you use it while you sleep), the tube last a long time and the price is good
Heather G.
Phoenix, AZ
5 reviews
I use this as a spot treatment for cystic spots. It reduces the size, redness and relieves the pain very quickly. I'd say it improves spots 40% faster than using nothing at all. Definatley worth the money and it lasts a long time since a little goes a long way.
Amber A.
Chesterfield, MI
101 reviews
Beauty Junkie Expert Level 2
Besides the fact that it burns when you put this on a blemish, it is amazing. You will notice in a day a size difference. Pretty much zaps the blemish and dries it up.
Dolly H.
San Jose, CA
77 reviews
I bought this hoping that I could get rid of acne or at least reduce inflammation. Unfortunately it did nothing and I saw no difference after using it. Useless product and not worth the money.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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