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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,321 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10321)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Abby G.
Menomonie, WI
50 reviews
I was blessed with dry skin so I don't have much acne but when I do, it's stubborn and won't go away. Applying a dab of this treatment dries out the pimple and usually by the next day it is gone.
kennedy R.
Vinton, VA
42 reviews
Beauty Junkie Expert Level 1
Whenever i see a zit starting to form i immediately put this stuff on the problem area and by the next morning the zit is either gone completely or reduced dramatically!
Stephanie A.
Jacksonville, FL
115 reviews
I had a terrible bout with acne and i started using this product which worked for me after a couple weeks use. I find that you need to use a very small amount or it will bead or peel of your face as you try to massage the product on your skin for better absorption.
Lindsay S.
Odem, TX
98 reviews
Beauty Junkie Expert Level 1
I really liked this spot treatment! It helped to minimize and diminish any random breakouts within a couple of days! Effective and I will definitely continue to purchase!
tameka c.
Rock Hill, SC
148 reviews
Beauty Junkie Expert Level 4
This is an okay spot treatment. It took a few days to see any real results. I have had quicker results with toothpaste. I wouldn't repurchase this spot treatment again.
Jelly L.
75 reviews
Although i think its a bite expensive, when i first tried this it really worked well, burned a little but it worked and fast, and all you need is a little.. great product
Amy T.
26 reviews
This product does dry up acne. However, I have sensitive skin so it also dries up my face in the process. It also takes about a week or so before the acne is truly gone.
Kristen M.
164 reviews
Beauty Junkie Expert Level 4
I've used this before and sometimes it works really well, but then there are other times when it doesn't help me at all, so I haven't found it to be incredibly reliable.
Priscilla L.
California, PA
10 reviews
I have oily acne-prone skin and I use this every night as a spot treatment on problem areas and it works great. By morning they are reduced about 90% and by the next day they are gone completely.
Alexandra C.
Winter Park , FL
299 reviews
Beauty Junkie Expert Level 5
This stuff is a great preventative product. If I start to see a blemish begin I start applying this. It is not as strong at getting rid of an already existing blemish.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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