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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,303 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10303)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Patrick D.
21 reviews
I tried this item when i was desperate of trying to get rid of a specific pimple and I'll say it did work but it toke about a week to go away completely. I really do wish if it would work much faster.
Mk P.
Coldwater, MS
60 reviews
Beauty Junkie Expert Level 3
I use this from time to time of course with my daily face regimen and it seems to help. I cannot say that it does the job, but it does help relieve bumps and redness faster than healing by themselves.
Karianne F.
Huntington, WV
22 reviews
Beauty Junkie Expert Level 2
I use this when I get the occasional break out. I usually take showers at night and apply this before I head to bed. When I wake up, my breakout is noticeably smaller and gone within a few short days
Latonica R.
Bronx, NY
13 reviews
This spot treatment really works. It does have salicylic acid in it, but this treatment works like a charm:) I am seriously satisfied with this product but I wouldn't call this one of my holy grails.
Carol M.
Bronx, NY
51 reviews
Beauty Junkie Expert Level 1
This is my Secret weapon for curing it honey, just a little dab and you could even smell the alcohol. It works so well. Somewhat harsh but at the same time gentle perfect for a spot treatment. I've bought this several times
Zulianna P.
Miami Lakes, FL
61 reviews
This stuff is great! I used to use it all the time when I had really bad breakouts. I would literally put it on before bed and the next morning the pimple would shrink and also not look as red amazing!
Alaha A.
Philadelphia, PA
90 reviews
Honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would
Tarundeep K.
S Ozone Park, NY
56 reviews
Beauty Junkie Expert Level 2
Used this on a pimple and it dried up within thw first day of using it. Definitely recommend this. My dermatologist gave me a acne gel with 5% benzoyl peroxide and that didn't work as good as this did.
Jordan S.
Levittown, PA
304 reviews
I've used this product a lot in the past. It does work but I felt the more I used it the more akin problems I had. Fair price. Packing made easy to bring along on the go. Recommended but not excessive use.
kimmy c.
West Hartford, CT
9 reviews
Best and I mean best spot treatment ever!! Every time I have a pimple I put it on at night and in the morning it's barley even there, I even use it under my makeup so through out the day it's working
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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