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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,309 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10309)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Fatima C.
Gardena, CA
396 reviews
I usually have clear skin; but before my periods i break out om ny chin and cheeks; this product clears those out within 24 hrs!! I would recommend this for mild pimples and acne arising due to hormonal changes; don't think it should be used on severe acne.
Julia B.
517 reviews
Beauty Junkie Expert Level 5
This works great! I love when i wake up in the morning and my zits are all dried up, I use this after I wash my face and do my whole night routine, it makes my zits small and dries them up over night! I would totally recommend!
Catherine J.
Chicago, IL
30 reviews
This is a great acne product. If I feel a pimple coming, I just put a dab of it on in the morning and within a couple hours the pimple goes away and there is no more redness! If I use it on an existing pimple, it starts drying it out right away and it is gone within a few days. I have been using this product for years and will always have it in the house!
Laken D.
Hattiesburg, MS
19 reviews
Beauty Junkie Expert Level 1
I like this product however I wish it worked faster. It was okay but it didn’t quite meet my expectations. The packing was simple. It was effective after a couple of uses, but I wanted a formula that was more effective.
Sarah H.
49 reviews
This product is okay. It burns my skin a little and probably would be bad for sensitive skins. I instead constantly repurchase the other Clean and Clear treatment--I believe its persa 10 gel or something to that affect.
Haley S.
La follette, TN
9 reviews
It helps dry out the pimple. It has a smell but not strong. I bought it from Walmart. It lasted a long time. I am a repeat user. It's a good price for the amount of product. I would recommend this to people who have acne
Katoria H.
Seaboard, NC
109 reviews
Beauty Junkie Expert Level 4
I've been using this product for a while now. Whenever I get a blemish and use this product consistently, it goes away in no time. I'm not a fan of the smell but it's worth it for a product that dries up my oily spots
Tessa B.
105 reviews
Beauty Junkie Expert Level 4
I find this product works great. when I'm having a break out i put some of this on the spots at night amd when i wake up in the morning its practically disappeared. redness gone amd no longer inflammed looking. so good!
Jessica A.
Winchester, VA
79 reviews
Beauty Junkie Expert Level 2
I do not get acne that much but once in awhile something will pop up. I tried this and the smell was so strong that it turned me off. I also did not notice my acne going away because of this. Overall I would not recommend
Brittany A.
38 reviews
I recommend this to anyone. This tiny tube has lasted me over 2 years, but I also don't have bad acne. This spot treatment feels great - it has a cooling sensation at first and then it's almost as though you can feel it cleaning the toxins from your pores.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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