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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,294 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10294)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Vanessa M.
35 reviews
Beauty Junkie Expert Level 1
I used this for random bumps and spots that seem to appear over night. I love this treatment. A little smell to it and you can feel a cool somewhat tingly sensation on your face but I like to think that's how you know it's working and getting the job done!
Jasmine A.
Rochester, MN
97 reviews
Beauty Junkie Expert Level 4
This was my life line in High school! I use to get very bad pimples and this would reduce the size and redness over night! By day two it would be gone completely. Now in my 20's i don't see so many pimples, but i keep it close at hand for any breakouts!
Teresa A.
Seaford, NY
38 reviews
Beauty Junkie Expert Level 1
This product is my go to for pesky little pimples that you can't get rid of. I put some on my trouble spots before bed and wake up the next morning with those spots looking better that they would with any other cleanser. Highly recommend this product !!
andrea J.
Las Vegas, NV
29 reviews
I love clean and clear, I went out and bought the whole acne fighting kit. I had bad acne scars also and the kit made a big difference! I recommend this if you have bad acne. This spot corrector has a cooling feeling that won't leave your skin irritated.
Holly Ann R.
13 reviews
This stuff works great! The second I can feel a pimple coming on, I apply this on it almost immediately! I love that it's a squeeze tube and very easy to travel with. I love that you can find this at any store! It's affordable and best of all it works!
Sana B.
48 reviews
Beauty Junkie Expert Level 1
In the beginning, this product was my holy grail! It got rid of my scars and shrunk the size of my acne overnight. As I started using it more, I noticed that my face wasn't reacting to it anymore. The scent smells like alcohol and it sting when a lot is applied.
Tamanna H.
Ashburn, VA
117 reviews
I love this product because it actually works. It reduces the size of the pimple by half the next day. I usually use this before going to bed and if needed during the morning if I don't have to wear makeup. This is a nice formula too because it's clear. I sometimes use powder over it if I have to go out real quick. Not harsh or irritating at all!
Larkin D.
Napa, CA
21 reviews
Beauty Junkie Expert Level 1
Good for small blemishes. I wouldn't say it works overnight but it works. It was personally harsh on my skin. It was my first time using it, and I don't think ill sure it again. It was pretty disappointing. I would not buy it again. Though I have heard it has worked for some people. 
Alycia W.
Naperville, IL
41 reviews
Beauty Junkie Expert Level 2
The back of this package said to apply 1-3 times daily. I applied twice before bed, Once when I got home from work and right before i went to sleep. I saw noticeable differences in the morning. My acne was not gone but it was significantly better.
Bethany B.
27 reviews
Love this acne spot treatment, I apply it when I feel a bump coming up and within a few hours its gone... I also like to apply it before bed and wake up with a fresh and clean face!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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