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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,297 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10297)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Anna B.
17 reviews
Beauty Junkie Expert Level 1
This product is one that's been on my shelf for a while. I only bought it because of the bold claim on the packaging, but this really works! It's helped me so much to clear my skin and just look so much healthier!
Kaylie J.
32 reviews
Beauty Junkie Expert Level 1
I’ve been using this since I could remember, when I first started developing acne in middle school I used this and absolutely loved it. It has always got those pimples and vanished them before the blink of an eye!
Alexia R.
100 reviews
Beauty Junkie Expert Level 2
Horrible! I tried this for my acne and it burned my face! I was way to harsh for my skin! It was at a good price but it was not effective, first time user and won’t be using it again! There is a big room for improvement and I do not recommend it!
Alexandra R.
Carpentersvle, IL
88 reviews
Beauty Junkie Expert Level 2
My best friend recommended this to me. We don’t get a lot of acne but here and there we get that one pimple. I gave it a go and applied it at night on one pimple, and the next morning it was definitely a lot smaller. Another overnight application and it was gone. It kind of stings a lot, but it subsides and it’s worth it! The tube is a little expensive and it’s tiny but trust me, a little goes a long way.
Michele B.
106 reviews
Beauty Junkie Expert Level 4
If you use too much, your skin will dry out quickly. However, I used this about twice per day and saw results. It doesn’t prevent future breakouts but did clear up individual pimples.
Emma R.
St Paul Park, MN
92 reviews
Beauty Junkie Expert Level 2
This acne treatment definitely reduces redness so much and the appearance of acne just overnight or in a couple hours! I didn’t think I would like this as much as I did but its a definable difference very quickly
Rosemarie S.
Pittsburg, CA
88 reviews
Beauty Junkie Expert Level 3
If there was a 10 star I'd use it. This is my holy Grail I have this in my bag no matter where I go and it is a top priority in my makeup kit. It works within seconds and is perfect to apply as a barrier between makeup and skin my clients love this it leaves a tingly feeling but once you wash your face those blemish spots are almost invisible.
Raven M.
259 reviews
Beauty Junkie Expert Level 3
This product was easy on the skin. Did not contain a chemical smell and it was the easiest to apply to the affected area. The texture of this spot treatment felt almost gritty, but not terribly noticeable. I think the packaging was simple and appealing in the see-through box. It is reasonably priced compared to it competitors I would definitely buy again.
Fatima C.
Mineola, TX
72 reviews
Beauty Junkie Expert Level 2
I love all Clean & Clear products because they maintain my skin clean and clear!! I wanted to try something to make my pimples/ blemishes disappear or make them less noticeable. I went to Walmart and purchased this product and I loved the result. It made everything less noticeable and in a couple of days I was acne free!! Totally recommend it!!
Bri S.
142 reviews
Are use this for a while but didn’t really feel like it was very effective. It was affordable but somewhat disappointing product. I did not meet my expectations that I wouldn’t recommend. I won’t be buying again.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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