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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,328 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10328)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Alianna H.
Hastings, NE
36 reviews
Beauty Junkie Expert Level 1
This stuff is definitely a regular in my skincare routine. I'm pretty dry skinned with blackheads on my nose, and I use this product specifically for them. It does an amazing job of keeping the blackheads at bay without drying out my skin. It's an awesome product, and I'll be using it forever.
Andréa G.
171 reviews
Beauty Junkie Expert Level 2
The best stuff for those rare monster pimples! This stuff works right away, you can feel it drying up all that junk in your pores and by morning your pimple is history! It can be found in your local drugstore and I would highly recommend keeping a tube in your medicine cabinet.
Chrysthel S.
33 reviews
I used this once before and I had an awful experience with this product. I broke out even more and it dried out my skin making it chaff practically. Talk about OUCH. Anyway i would not recommend this product if you have very sensitive skin as well as dry to very dry skin.
Sonali B.
Victorville, CA
70 reviews
Beauty Junkie Expert Level 3
This stuff is amazing! it works amazing on any types of pimples or marks. The best thing to do is apply it to the problem area right before bed and you will see such a difference in the morning!
Alisa P.
Antioch, CA
19 reviews
Beauty Junkie Expert Level 4
I have very oily skin so it's very acne prone. I started using this and i found it didn't help much at all. It felt very sticky on my skin and took forever to dry. Would NOT recommend using before putting your makeup on in the morning because I found it peels as it drys.
Cassi M.
222 reviews
Doesn't treat really difficult problem spots over night, but will help if you catch a zit in the early stages. Apply at night before bed and not in the morning. If you try to wear makeup over it, it'll get flaky and super obvious that you're wearing acne spot treatment.
Lauren B.
Radstock, NC
9 reviews
I've used this product for years and it always works for me when certain conditions are met. Firstly, you can't pick at the spot at all. Secondly, it can't be hormonal/ that time of the month. At least for me, if it is hormonal, nothing can stop a spot from rising, but this product does help control the bump and redness
Evelin  L.
Los Angeles, CA
43 reviews
I used this product once, at the beginning I felt it working but then after a while it wasn't giving me the results I was expecting. It's an ok product .. I could say I guess. But for me it didn't really work as well as my friend who recommended it to me , said it would.
Michaela T.
Cantril, IA
111 reviews
Beauty Junkie Expert Level 3
I love this spot treatment. I tend to get monthly breakouts in the same spots. Using this on those spots usually prevents them from popping up at all, and if they do, they are smaller and sorter lived.

In general, my brekouts clear up faster with this spot treatment.
Mariela R.
Escalon, CA
41 reviews
Beauty Junkie Expert Level 1
I bought this product to remove acne scars. I did notice that my acne would clear up when I spot applied it. It does burn a little bit when you apply it, but I do not think it is bad because I know that the product is doing its job. That was the only side effect and it did not dry my skin. 
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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