Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,301 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10301)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Pei Chan M.
Brooklyn, NY
3 reviews
This product used to work but it seems the newer formula doesn't work as well. It also sometimes burns when applying but otherwise smells nice and dries quickly. It doesn't dry out my skin or give me any adverse reactions. I would recommend if you're looking for a quick fix.
Carissa L.
Milligan College, TN
13 reviews
Only acne treatment I've ever used that works. Uses salisylic acid as active ingredient so it doesn't cause me skin irritation. It's affordable and works fast! Would recommend to anyone, especially those with somewhat sensitive skin.
Lena C.
Westwego, LA
275 reviews
Beauty Junkie Expert Level 4
I just started using this after advice from a friend on YouTube about how great the product is. The tube has changed from the original but that's ok I prefer the plastic. If I have a situation at night and put this one 9 out of 10 times it will be much smaller. Almost unnoticeable.
Shannon B.
Waukesha, WI
6 reviews
I like this product because it dries up my zits very quickly. It usually gets rid of them in a couple days. It does burn a little bit but not too bad. That being said, I probably won't be repurchasing because it doesn't do anything a little bit of hydrogen peroxide doesn't do.
Melissa P.
10 reviews
I like this medication, but I dislike how it claims that 100% of people saw results by the next day. I believe that claim is partially because as acne takes it's course, of course it's going to start improving day-by-day. When using this product, I was unsure if it was actually helping or if my acne was just taking it's regular healing path despite the help of this treatment. I would like to think that it helped speed the recovery process just a little.
Yoselinn G.
San Diego, CA
20 reviews
This helped me a lot Through my first severe acne case it's very affordable and easy to find as well. I use this every time i seem to get a new pimple . I highly recommend it and it totally met my expectations I'm actually running out of mine so I need to buy a new one soon
Katie M.
Tampa, FL
6 reviews
I've found that this product works better for me than the Lush Grease Lightning that I was using before. This product works quickly and it's perfect for over night spot treatment. It's a small container, but it has lasted me forever. I would recommend this to anyone who gets blemishes, but not for those who suffer from severe acne.
Emerson R.
95 reviews
Beauty Junkie Expert Level 2
if i could give this 0 stars then i would. this product did absolutely nothing for my acne or breakouts and severely disappointed me. i feel like this product even made my breakouts worse. i'm not sure if it was the  salicylic acid in it but whatever it was just didn't do it for me! 
Ally B.
Lexington, KY
57 reviews
This stuff dries out the blemishes so that they eventually go away. You have to keep with your skincare routine in order for it to actually work, but it is worth it. This stuff works really well. Plus you only need to use a little bit of it so it ends up lasting you quite a while.
Michelle A.
Tacoma, WA
11 reviews
Beauty Junkie Expert Level 3
I have bad acne so I use Clean & Clear Advantage 3 Step to keep it in control. I use the spot treatment almost every day. At night when I use it, by the time I wake up the next morning the pimple is way less red, and with one more use the pimple is gone. Love this spot treatment!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

BackInfluenster Cashback
Clean & Clear® Advantage® Acne Spot Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.