Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,295 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10295)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Gabbi N.
Colorado Springs
3 reviews
Really dried out my skin. Burned a bit upon application,smell is strong and leaves a weird tight feeling on my skin, as far as the actual product working as a spot treatment it didn't deliver results. It just dried out my skin and burned.
lisdeys b.
Westminster, CO
66 reviews
I dry those unwanted acnes on my face, I also use the cleansing gel. I have used this for a while, since my skin tends to have a lot of acne, and this controls me in the apparitions. This product is very generous with your skin, at least with mine is.
Candace S.
Barnet, VT
169 reviews
Beauty Junkie Expert Level 4
I don't get a lot of break outs, just a little bump every once in a great while. But when I do get one I just put a little dab of this on it before I go to bed and when I wake up it's just about gone. Sometimes I'll have to do it two nights in a row. But it works really great for me!
Molly Z.
Vernon Hills, IL
53 reviews
Beauty Junkie Expert Level 3
This is my go-to spot treatment. It works quickly and I like that it is a clear gel rather than white like some other spot treatments I've used. I have oily skin and this works great for me, but it may be too drying for someone with normal/dry skin (or just sensitive skin in general).
Megan R.
Buckhannon, WV
15 reviews
I LOVE this for when I am PMSing and have a ton of break outs. It's used for spot treatment, but my acne tends to find the spots where I don't use medicine, like my eye brows or close to my lips. Therefore, I use this all over, rather than a spot treatment. When I do this, I like to use a good moisturizer so I don't over dry my skin.
Amanda B.
4 reviews
Love this product!!! I use it when I feel a pimple coming on or already have a BIG pimple but I always always always use it after I wash my face and let it dry completely & after that I put (O'lay active hydrating beauty fluid lotion) let that dry also and than put the Spot Treatment only on my bigger problem area if I have any at all!
Ave H.
6 reviews
I have never had acne, and only occasionally break out (2-3 spots). I have sensitive combo skin, and tend to break out around my temple area.

Because I don't have acne, and only occasionally break out this works a lot better because it spot treats. I just dab this on a developing spot, go to sleep, and after 1 or 2 night its gone!
Anne R.
San Diego, CA
19 reviews
This product worked for me but I hate the dark scars they leave behind. I'm not sure if anyone else experienced this but it's definitely not worth it. I rather have my pimple take its own course than have dark acne scars all over my forehead. I eventually stopped using this product.
Emerson R.
95 reviews
Beauty Junkie Expert Level 2
if i could give this 0 stars then i would. this product did absolutely nothing for my acne or breakouts and severely disappointed me. i feel like this product even made my breakouts worse. i'm not sure if it was the  salicylic acid in it but whatever it was just didn't do it for me! 
Melissa P.
10 reviews
I like this medication, but I dislike how it claims that 100% of people saw results by the next day. I believe that claim is partially because as acne takes it's course, of course it's going to start improving day-by-day. When using this product, I was unsure if it was actually helping or if my acne was just taking it's regular healing path despite the help of this treatment. I would like to think that it helped speed the recovery process just a little.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

BackInfluenster Cashback
Clean & Clear® Advantage® Acne Spot Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.