Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,543)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Daisy R.
Palmdale, CA
19 reviews
This stuff works miracles. I put some in my problem areas before I go to bed after I cleanse my face. 89% of the time I wake up & my problem areas are either feeling smooth , looking BOMB , or are completely clear
Melanie C.
Chattanooga, TN
122 reviews
Beauty Junkie Expert Level 4
Haven’t had to use to this stuff since high school but it is a lifesaver in an overnight miracle worker on sits like I said I’m 35 so I don’t really break out enough to own this but back in high school I had two bottles all the time and it worked and I wore darlin’ them on my blemishes and woke up and they look like almost gone overnight every time the staff is great
Hannah B.
Manhattan Beach
28 reviews
Beauty Junkie Expert Level 1
I love this spot treatment. It works so well. I bought it at a time when I was having some acne problems and it was a life saver. I've heard that for some people it stings, but for me it's pretty gentle.
Garyondris R.
17 reviews
Beauty Junkie Expert Level 3
Reduces redness in less then 4 hours
-cheaper then other products
-helps from more acne from coming
-works better if you only use clean & clear products
Cons -stings for about 5 seconds (but that's how you know it works)
-may run out fast
-if you use makeup over the blemish let the product dry before use or else when you put the make up on it will rub off the makeup and product.
Bottom line This product will work a lot better if you use clean and clear ONLY. This product works great!
I use it everyday and it really helps. If it is combined with another product if may cause a redness that will go away in a day
Elly L.
Anaheim , CA
144 reviews
Beauty Junkie Expert Level 3
Purchased at: ULTA
Perfect for the small pimples that start to come out and it really works. I don’t mind the feeling of it on just spots on my face because to me it’s not too thick
Alex P.
2 reviews
This product is great for getting rid of minor acne without being overly irritating to the skin.  I prefer Neutrogena's acne products overall, but I can't find the one that has salicylic acid in it, so I've switched to this product.  I have very minor breakouts occasionally, so I use this to treat them. I can't speak to how effective this is for overall acne or severe breakouts.  
Christy H.
98 reviews
Beauty Junkie Expert Level 4
This product works pretty well for me on smaller pimples but it doesn't work as well on cystic acne spots and if I use it too much it does cause my skin to become very dry any peel-y
Morgan L.
Alma, AR
27 reviews
Beauty Junkie Expert Level 1
I LOVE this stuff!! I have typical teen acne and this zaps the zits as soon as I feel it come on! I bought this at Wal-Mart and it was cheap, too! Can't beat it!
Callie F.
4 reviews
I used this product so much because my acne was always getting me down and for the most part this would work! Not 100% but it really got the redness down which was a big plus for me!
Em G.
26 reviews
Beauty Junkie Expert Level 1
GREAT for zapping an incoming pimple over night. Though, if you have sensitive skin beware it can be very irritating. Recommend only using in moderation. But overall good product and is a staple in my household.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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