Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,616)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Adriana G.
Milwaukee, WI
29 reviews
This does help pimples come out and reduces size of pimples after a few days. It does dry out my skin if used multiple times a day. I was expecting this to work a bit quicker which is why I'm not very satisfied. The packaging is very convenient since it's a long tip you can easily dab the product on your pimple. I would also recommend just letting the gel sit on the area than smoothing it over with your finger. It seemed to work better that way. Besides that it's a great price and lasts a long time.
Sarah H.
13 reviews
My go to topical cream. It even burns when you get it on those stubborn pimples. So you know it is working. A little goes a long way. It definitely reduces breakouts in just 1-2 uses. 
Jeana F.
Wayne, NJ
16 reviews
Beauty Junkie Expert Level 1
This was a very ineffective product for me. It not only caused more breakouts and made my existing pimples worse, it even dried out my skin. I do not recommend that anyone struggling with acne buy this product, as it is a waste of money and worsens your symptoms! 
Lynn E.
20 reviews
Beauty Junkie Expert Level 1
The best drugstore spot treatment. This is even better than clearisil. It is very cheap and defiantly worth the money. It has pretty nice packaging. Nothing too fancy. It is very effective, once you apply it, in the next day it is gone. Perfect
Tiffany G.
San Antonio, TX
266 reviews
Beauty Junkie Expert Level 4
I love this product. When ever I have a pimple I spot treat it and it goes away in 2 days. The price is cheap anywhere you buy it. I recommend to treat at night.
Marina B.
New York , NY
103 reviews
Beauty Junkie Expert Level 1
I love this product. It is one of the only spot treatments that actually works. I put it on overnight and the pimples as gone. I definitely recommend it. The applicator is easy to use and allows you to put on just enough. That means it lasts me a long time. 
Marissa R.
Philadelphia, PA
60 reviews
My wife and I absolutely love this product. We will use this whenever we feel a pimple coming on. Great spot treatment to get at a drugstore. Have repurchased several times.
Sandra D.
233 reviews
Beauty Junkie Expert Level 5
This product really seems to work for me. I apply a dab of it as soon as I see a pimple start to surface and it usually dries it out before it can become a big problem. I'll apply it at night before bed and once or twice throughout the day and before my makeup. Word of warning though this stuff can and will dry out your skin if you use it to much. It is exactly what it says it is, a SPOT treatment. So don't go smearing it on your entire face unless you want a serious case of the flakes! Ick
Chloea' F.
Statesboro, GA
41 reviews
Purchased at: Walmart
I tried this and the product did last a long time! However i never noticed a difference when using it. the ingredients might just not work with my skin as i know others who love it.
S B.
18 reviews
I was wowed by this product. I have a party to attend to in a week and i had some breakout and i use this producct and it did really do its job. I work for me really well. I will
Surely use this product everytime i have those days. Breakout day.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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