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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,296 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10296)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Emily B.
Ellijay, GA
14 reviews
I used this product for a while and it worked well at first. Eventually, it stopped working as well which happens with a lot of acne products so I was not surprised. I also felt like it was very harsh on my skin and it did not have a pleasant smell but that is to be expected.
Evelyn I.
Westminster, CA
92 reviews
I love this product! It will shrink the size and redness of acne in one day. I first bought it to treat new spots, and it worked so well I now use it everyday as my regular acne treatment. I have always had moderate acne, but I haven't had a single breakout since I started using this product. I've tried everything, including Proactive, but all of the other products...
Read the full review ›
Natalie W.
Burke, VA
16 reviews
I love this product! It really does help with ridding your face of acne and reducing the possibility of blemish pop ups. The packaging is realistic and met my expectations. The price is super affordable! This is on my monthly buy-list and I will definitely continue to get it!
Anna H.
1346 reviews
Beauty Junkie Expert Level 4
This is a good product but it didn't work for me. It irritated my skin but when my fiancé used it he had no problems in fact it cleared up his skin so fast I was jelouse! All I could say is try it for your self but beware if you have very sensitive skin!
Virginia R.
Miami, FL
20 reviews
This is a great product. For those pimple that suddenly appear, you just put a little bit there and you can see the results the next day, I've bought it a couple of times since I don't have a lot of acne problems, however I think it does work great. I definitely recommend it
Mikayla W.
159 reviews
This product helps clear up pimples fast! Just apply a small dab on existing pimples and they will clear up within a day or two. I love this product for when I have a sudden pimple appear and want it gone quick. A small dab goes a long way with this product. It doesn't really help prevent break outs but when one happens unexpectedly, this will help get rid of those unwanted pimples quick.
Haylee S.
16 reviews
Beauty Junkie Expert Level 1
This product is great to use if you spot a pimple and need it gone quick. The packaging is nice but could be a little better, because it's hard to control how much product comes out. This works very well, but sometimes it dries out the skin around the pimple. I'd recommend to put this on a problem spot before bed and then moisturize in the morning. I'd definitely recommend this to a friend.
Allison L.
Corydon, IA
21 reviews
This clean and clear product is by far my very favorite product that they have, it works fast, it's very easy to apply, it does burn a little, but its more or less a cooling feeling not a actual burn, but that just means it's working and is sinking into the pores, works instantly! If you put it on the night before, wake up the next morning and there is a noticeable difference in your skin
Purple d.
Storrs, CT
107 reviews
Beauty Junkie Expert Level 4
I absolutely love this product! Although it doesn't work as fast as it says it would (4 hours), it definitely works. I had two bigger than normal pimples and applied this three times a day and both pimples were gone by the third day. For $10 you really do get so much out of it.
Alyssa K.
211 reviews
Beauty Junkie Expert Level 5
This works great. I do not get acne too often thank goodness, but whenever a lone pimple pops up or I feel one developing under the skin, I pop this on before I go to bed after my skincare routine and it is better by morning! It is drying, but that's what moisturizer is for
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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