Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,548 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10548)
Q&A (464)
Media (122)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Marley P.
228 reviews
I've been using this spot treatment for at least five years, and it works great. I've tried other spot treatments that use benzoyl peroxide instead of salicylic acid like this one, but they have not been nearly as effective. The only problem is that my skin gets dry and flaky wherever I apply it.
Sydney K.
Great Falls, VA
11 reviews
Beauty Junkie Expert Level 1
Definitely helps me a ton with acne and pimples! It can be a bit drying if you use it a lot, so I recommend using it right before bed and maybe not everyday. I've re-purchased this item time after time and it is the fastest working acne spot treatment I've ever used, and I've tried a ton! I'm only giving it 4 stars because it can cause drying and peeling if you over use it.
Misty C.
59 reviews
Beauty Junkie Expert Level 3
So I've never had bad acne, I actually have really clear skin but whenever I got my first zit I had no idea what to do. I walked around Walmart to try and find something and this product is literally life. when I feel a zit about to appear, all I do is put this on it and like magic it's gone. I'm sure the results vary but for me it works wonders, yesterday I had a really irritating zit and I put this on there and within hours it was gone, by far my favorite acne product.
kelsey S.
12 reviews
Beauty Junkie Expert Level 1
This has been a "go-to" item for me since high school - i'm now 25 and still using it. I see a noticeable difference over night, or after a few hours of applying it. Be sure to moisturize before or after use (i moisturize before) since it can be drying to the skin around the affected area.
Nicole F.
2 reviews
Consistency: This is a clear cream consistency.

Effectiveness: This works like a charm! I have applied it to many acne areas and the redness has gone away within 1-2 days. It does dry out the skin some, but that is to be expected for me.
There is also a slight smell, like a normal acne product.

Purchased at Walmart or Target - I have seen it anywhere you can buy this brand though.
Gabriela D.
Miami, FL
261 reviews
Beauty Junkie Expert Level 4
I've been using this since I was a teen going through changes. It helped me out a lot, it works fine, but you have to be careful to apply it only where you need it cause it dries the skin out a bit, so have that in mind. It stings a bit when you first apply it. I normally apply it at nights and in the morning I can definitely see a difference.
Maggie G.
Selinsgrove, PA
19 reviews
I've been using this for years. It works so fast at clearing acne. I love it and it's relatively gentle on the skin. I think it's worth the money to buy it and the product is found in many stores.
Shawnee H.
N Myrtle Bch, SC
296 reviews
I don't get pimples very often, but when I do I put some of this stuff on it before I go to bed and when I wake up, it's almost completely gone. Definitely a great product. I wouldn't recommend using as a daily acne treatment though because it is very drying. Perfect for spot treatments.
Angelique Z.
32 reviews
I've been using a lot more make up since it's been colder outside and my face has been breaking out more so I decided to give this stuff a try, and it works !! I notice the redness goes away within a day or two at the most. I only use it twice a day, morning before my make up and at night after I wash my face. I have noticed that sometimes it does sting if a spot is open. Other than that, I have no problems.
Cheyenne P.
10 reviews
I absolutely love this product. It cleared up any break outs quickly and was easy to use. I got it off of Amazon, but you can also get it in stores like Target and Rite Aid. I found this product after researching good acne treatment products that were gentle on skin and not too expensive.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

BackInfluenster Cashback
Clean & Clear® Advantage® Acne Spot Treatment

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.