Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,703)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Erika J.
Jacksonville, AR
318 reviews
Beauty Junkie Expert Level 4
This works okay. On my skin i feel like it didn't do much on making the pimples dry. I used a couple of times it's very affordable but it didn't do what I expected it to do.
Raelynne H.
12 reviews
Beauty Junkie Expert Level 1
This product was okay . It dried
Out my acne but I feel didn't
Solve the problem there was still a lot of redness and kinda made me itchy. It didn't meet my expectations really. Up to you to try it .
Nikki D.
Morgantown, WV
27 reviews
Beauty Junkie Expert Level 1
Dries up any imperfection but dosent work over night it's good to zap zits but toothpaste works just the same (white paste) it's nice packaging but small u don't really need a lot just apply a dab.
Ashley M.
Carrollton, TX
14 reviews
I have used this product for YEARS and absolutely LOVE it. Anytime I notice a breakout starting I apply this to it and the next day the redness and swelling has gone down.
Karri K.
82 reviews
Beauty Junkie Expert Level 1
It really does work ! I have been using this since 6th grade . Used right before any date ! Super affordable great for men and women of any age ! I buy at any drug store .
Morgan T.
Columbus , OH
23 reviews
Beauty Junkie Expert Level 1
This product just dries out my skin and didn't really take care of any acne issues I have been having. This was my first time using it and probably wouldn't purchase again.
Emily N.
Dublin, OH
80 reviews
Beauty Junkie Expert Level 1
Dries out my skin but doesn't necessarily minimize skin blemishes. Plenty of product though. Does not sit well under full coverage foundation without plenty of time to dry.
Emily V.
56 reviews
Beauty Junkie Expert Level 1
Works for a pimple spot treatment. Dries it out. If you keep this stuff on it the blemish will dry right up. Doesn't prevent blemishes. Just a spot tx. Can be very drying.
Rebecca S.
Spring Branch, TX
106 reviews
Beauty Junkie Expert Level 2
I'm not surprised that this product made it to the top of the list. I don't have bad acne but whenever I get a blemish, I apply this product and I feel it immediately working.
Katie M.
Las Cruces
15 reviews
You put this on overnight and your zit is noticeably smaller with less redness. I break out a lot so this helps me target those big, self-esteem crushing blemishes you know everyone is staring at.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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