Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,573)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Vivian T.
6 reviews
The first time I used it, it worked really well. I wantes to try it because many people recommend it for breakouts. When i kept using it, it didn’t do much for my skin later on, I dont think I would purchase this again
Anna R.
286 reviews
Beauty Junkie Expert Level 3
I love this stuff. If you have a pesky pimple, apply a small dab to it and it will be gone soon after. The small travel size packaging is easy to carry with you in a wallet or purse. It's a great product for a quick fix!
Ashli P.
Thackerville, OK
92 reviews
Beauty Junkie Expert Level 3
This is pretty good acne serum. Smells great!!! Good for major breakout but i found another serum that seems to work a lil better for every day and I seem to have to use a lot of this and it doesn't last me very long. So will use this for nighttime only during a major breakout.
Kristen N.
69 reviews
Beauty Junkie Expert Level 1
As far as spot treatment goes, this seems to be highly effective. I've tried a bunch, but none seem to work as quickly. It does tend to dry out skin pretty quickly, so apply with caution.
Amy M.
7 reviews
I love this product! If i have a pimple that showing over the surface, I put this cream on over night and it is ready to be popped in the morning. And i apply it after its popped, and theres MINIMAL scarring. it is a godsend. It is worth every penny. 
jean laura g.
Cape Coral, FL
121 reviews
Tal vez me bajaba la rojez un poco pero eso era todo porque igual me salía acné y no me ayudaba mucho mientras seguía allí así que para mi piel y mi tipo de acné no me ayudo mucho.
Lina C.
56 reviews
Beauty Junkie Expert Level 2
It works really fast for me.. I use it almost immediately after a break out and it erases the break out. I don't necessarily use the full 1,2,3 step system all the time but it still works.
Beckinstein S.
7 reviews
Beauty Junkie Expert Level 2
I've been using this stuff to spot treat acne for 20 years. I'm pretty happy happy with the results, although I feel like it has been slightly less effective for the last five years or so.
Carly K.
Murfreesboro , TN
97 reviews
Beauty Junkie Expert Level 4
I love love love this product. It's much more helpful if you buy the moisturizer and the face wash and use all three daily. But the spot treatment is super helpful for needing a quick fix
Miranda H.
Columbia, TN
112 reviews
Beauty Junkie Expert Level 3
Very good drug store spit treatment. I've gone through many tubes of this and will continue to repurchase. Great price and it does last awhile. I've bought this numerous times and I love it.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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