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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,329 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10329)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kaylie M.
25 reviews
Beauty Junkie Expert Level 1
This is the best product I have found for treating pimples in a short amount of time. We tried the gel version of this but didn't experience the same results as the cream version. It does leave a white residue on your face as it dries, but I am usually putting it on before bed, so it doesn't bother me. I really think this product shortens the life of a pimple and dries it up quickly!
Jordan S.
34 reviews
Beauty Junkie Expert Level 1
You get a lot of product for the price you may! I alternate between this and another acne cream and this one works best when I have small spots I want to clear up overnight. Easy to put on and doesn’t leave any residue on your face.
Angela R.
Potterville, MI
43 reviews
Beauty Junkie Expert Level 1
I love this stuff for my face. I was really weary at first about buying it and didn't think it would work especially with as small as it was. I was brutally surprised at how well it worked. I have adult acne and it pops up all over the place. This stuff is great for those troublesome pimples that pop up for no reason. Just a day here and there and and few days they are gone. Amazing!!
Chloe N.
12 reviews
I did like this product but if felt like it was bringing out my acne more! Also, when I would try to put on the skin, it would burn very much. I am not saying that clean and clear is a bad company, but this product was not for me!
Nadine I.
Staten Island
59 reviews
Beauty Junkie Expert Level 1
This stuff was good for mini pimples that I had like little bumps on the forehead or side of my face. It is a spot treatment but the way I used it is I would spread the treatment on my affected areas and let it dry down. It worked on minimizing the bumps and preventing more from forming, but I did not see a huge enhancement in my skin and the bumps were still there, just smaller.
Alyse M.
Litchfield Pk, AZ
210 reviews
Beauty Junkie Expert Level 3
I hate this stuff . It always rubs off and leaves a weird residue on my face and I really don’t think it has ever diminished any of my acne white head black head or small bump it has never done a thing .
Renee E.
11 reviews
Always clears up my pimples in a day or two. I have dry sensitive skin and this product doesnt seem to bother it to much. There is a little drying at the treatment spot but that is to be expected.
Haley J.
Clayton, NC
62 reviews
Beauty Junkie Expert Level 2
My favorite acne treatment ever!!! I have been using this product for years and am still amazed at the results! Makes every pimple disappear or at the very least reduces color and size overnight!!
bailey e.
4 reviews
This is a great product for tiny breakouts that are starting to form. It reduces redness and size super fast. The only thing is is that it can be drying if you use too much, so I recommend only using less than a pea sized amount.
Delaney M.
14 reviews
For this being so inexpensive, it’s amazing. It’s so good at eliminating pimples without drying out the skin so bad! I would definitely recommend this to others. Any time I run out of my MB drying lotion, I keep this as a spare!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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