Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #10 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,792 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,758)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Krystal M.
Moore, OK
35 reviews
Beauty Junkie Expert Level 1
This is my go to spot treatment for hormonal acne. I cleanse first with my clean and clear face wash and follow up with this spot treatment every night. By morning there is less redness and inflammation. Plus you can't beat the price for the amount of product!
Irene S.
Santa Clara, CA
30 reviews
I use this on pimples that come up that look like they can be popped right then. It helps to calm that down, immediately. I have also used these on angry ingrown hairs that help soften the skin and prepare to pluck that sucker out.
Makeia C.
Santa Monica, CA
13 reviews
Beauty Junkie Expert Level 1
Always my go to for spot treatment when I see a zit coming my way. I'll apply twice a day for that time and usually clears up pretty quickly. Light, non greasy and easy to keep... takes up little space in a makeup bag
Chelsea R.
Portland, ME
62 reviews
Beauty Junkie Expert Level 1
I always have a bottle of this hanging around. It kills those nasty breakouts and even ones that are just starting to come! This is the best crime for people who get the big pimple here and there with minor breakouts.
Kristen T.
Conroe, TX
36 reviews
Beauty Junkie Expert Level 1
I will get pop up pimples every once and a while so I like to keep products like this around. This one isn't the quickest, but it does work well. I like the packaging, it convenient and easy to use. I believe I purchased this at Walmart. I have recommended this to my brother and he loves it. 
Romina S.
Saratoga, CA
19 reviews
Beauty Junkie Expert Level 1
I used this for a few months but my skin is so sensitive, and this product made my face turn red. I bet it works, i have friend that ude this and works pretty good, but if you have sensitive skin, this is not for you.
Grace S.
27 reviews
Beauty Junkie Expert Level 1
This is great for the times when a pimple pops up. It kills the pimple in a couple days. It's easy to find, and Great for people who have acne breakouts. It's also small inconvenient for travel. Overall I recommend it
Rachel I.
Layton, UT
6 reviews
Beauty Junkie Expert Level 2
I like this product. I think it does a little to help my acne and breakouts. But I definitely noticed that it isn't curing it or working super quickly. A little disappointing. I would have hoped it was more effective.
Ella B.
3 reviews
Yes yes I am here today talking about...well...those annoying things that appear on your face without any invite..SPOTS, BLEMISHES, ACNE...whatever u want tocall them...they are a pain whatever the case!

I personally don't suffer from extreme cases but I know that teenagers...adolescent...reactions..whatever the cause I know what it feels like at the worse of times! This can have an affect on self confidence, the way you feel and future damage.

Firstly acne the worst of the is the occurrence of inflamed or infected sebaceous glands in the skin; in particular, a condition characterised by red pimples/spots on the face! All different skin types, sensitivity, allergies all have different ways and techniques that can be used while healing and helping the dreaded acne!

The main point I would like to infer is that however you treat the is the best for your own case...but my one tip for the whole circumference of situations is to stick with your treatment as the good results are normally made with persistence of the product or method!

Hope this gave u something to work off and maybe generate some ideas.
Melissa A.
Britt , IA
202 reviews
Beauty Junkie Expert Level 3
I hate acne, so a spot treatment is great for me! I get a zit, I apply and within a day the puffiness and redness is gone, with use the zit dries up and goes away!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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