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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,276 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10276)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Rafi M.
Jacksonville , FL
99 reviews
Beauty Junkie Expert Level 2
The only thing this product does is dry out the pimple and then it leaves a dark spot behind , however, I used multiple times just because I paid for it and was pricy I believe for such a product, I recommend it for people who don’t suffer from dark spots after pimples
elisabeth l.
5 reviews
Best spot treatment I’ve ever used honestly, I always keep it with me. When I’m out and have acne pop up I use it before I go to sleep and I’m 1-2 days the acne is gone
Nathan B.
Vineyard, UT
59 reviews
Beauty Junkie Expert Level 1
100% use this product every day on my blemishes. I can guarantee you a noticeable difference within 6 hours. It's not completely gone in that time frame, but you can definitely tell a difference.
Marissa F.
26 reviews
Beauty Junkie Expert Level 1
This product works great when you use it before bed. I had a couple zits and needed them gone by morning. Used before I went to bed and it had time to sink in and were close to gone by morning.
Alex L.
Mayfield, KY
99 reviews
Beauty Junkie Expert Level 3
I like this spot treatment, although it burns a little.  I find that it begins to shrink pimples overnight, although it is not a miracle cure.  I do like this better than many other acne spot treatments, though.
greenville , SC
21 reviews
Beauty Junkie Expert Level 1
This spot treatment is perfect to put on before bed, and sleep in. It always clears up any acne I have over night. It is so inexpensive for what it does. I take this product with me everywhere!
Brittani P.
Detroit, MI
93 reviews
Beauty Junkie Expert Level 3
This is one never leaves my home. It's helped so many of my troubled spots. I have bought it from Walmart and the packaging is ok. I would say the product is effective and I'd buy it over and over.
sinhy l.
Stevenson Rnh, CA
25 reviews
Beauty Junkie Expert Level 1
Didn't do much for my acne. I was not impressed with the product. Did not see any difference in the size or redness reduction.  The only thing I notice is that it dries out my skin a lot.
olea s.
11 reviews
this stuff kinda works, I mean I use it when I pick at my face when I break out and it kinda Bruns but it helps heal up my wounds quicker. so I would recommend this product for anyone honestly
Chelsea B.
2 reviews
Beauty Junkie Expert Level 2
love this stuff! This brand is the only brand of acne cleanser that helps keep my face clear and clears up and problems quickly! It is a little on the pricier side, as this is like 8 bucks for this little tube. However I like this stuff and will continue to buy it!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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