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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,328 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10328)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Isabell E.
Billings, MT
4 reviews
I use it every time I see a pimple. It reduces the size and irritation. Pimples that always grow and hurt and pop and scab instead go done and disappear when I use this a couple times a day.
Oriana O.
Santa Monica, CA
38 reviews
Beauty Junkie Expert Level 1
I have tried a lot of acne treatments but this is one of the worst ones. It does not work the way it says it does. If you put it at night, it will burn the spot you put it and wont take off the breakout
Catherine D.
14 reviews
Beauty Junkie Expert Level 1
I use this product after I was my face in the morning and I put it on my acne. I do believe it works well but it takes some time for the product to start kicking in, probably because your skin has to adjust to it. But it does work great!
Megan W.
Oak Hill, WV
347 reviews
Beauty Junkie Expert Level 3
I always keep acne on my chin and I don't even wear foundation. I've tried this before and I felt like it didn't work. It smells good but that's about it. It's a good price. But it just didn't work for me.
Rai M.
New york, NY
80 reviews
Beauty Junkie Expert Level 1
I used this when I had a wild beast of a pimple pop up. I think it was effective but I had also been using toner also. I felt like this really dried out the skin around the pimple and caused it to flake.
Sophia M.
116 reviews
Beauty Junkie Expert Level 2
Favorite acne spot cream! Works fast and efficiently. It’s affordable especially compared to the prestige brands. Zaps Your zits quick and is a quick fix for overnight needs for a morning flawless face!!
Rosario M.
Cranston, RI
54 reviews
Beauty Junkie Expert Level 1
I love this product my sister show me this product and I never will think work the way it did. I put the clear cream at night on my pimples the one that are white and the next day they arr literally gone
Kiley T.
27 reviews
Beauty Junkie Expert Level 1
I tried this product for about 2 months. It says it will clear up acne scars, but it really doesn't do anything. I wont buy this product again and especially for the price I paid for such a small bottle.
Kaitlan A.
1071 reviews
Beauty Junkie Expert Level 5
This is actually a realllllly good drugstore acne treatment. Can be a little drying but really does work well as on overnight spot treatment for pesky breakouts! Inexpensive and easy to find at a lot of stores.
Megan C.
Fontana , CA
45 reviews
Beauty Junkie Expert Level 1
I've been using this product for years! I just put it on at night where I have a pimple or I feel like I need it and usually by the morning it's gone or it's at least reduced the redness or irritability.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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