Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,512 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10512)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Tyler S.
Kennesaw, GA
16 reviews
Beauty Junkie Expert Level 3
This stuff is awesome! I had a huge zit that was under the skin & just poking through, and this helped to reduce it! It worked pretty quickly as well! I would buy this again & definitely would recommend to others!
Alisa H.
Raleigh, NC
14 reviews
This is amazing, I've used it for years, it takes away my acne and acne scaring in a week or less, it was amazing and it's very affordable. It's a very good product for people with acne prone skin or scarred skin.
Alma R.
16 reviews
Beauty Junkie Expert Level 1
This acne treatment is really good l usually just put a tiny bit of it wherever l have a pimple or acne marks and it slowly starts reducing it takes time to take effect but l definitely have seen results with it l would recommend others to try it out
Tory S.
Raleigh, NC
45 reviews
Beauty Junkie Expert Level 2
this is literally the greatest spot treatment product on planet earth! i’ve been using it for years and it helps my breakouts immensely. often times they are significantly improved over night, and this clears my pimples completely within 2 or 3 days.
Lindsay H.
70 reviews
Beauty Junkie Expert Level 1
This stuff is amazing. I’ve used this for years. Discovered it when I was in the horrible 7th dads acne phase and nothing else would compare to fixing my face. This works as well as my PRESCRIPTION ACNE MEDS! Not kidding. Would recommend
Lindsey C.
33 reviews
Beauty Junkie Expert Level 1
i used to swear by this but i think they changed the formula. it doesn’t work for me nearly as much as it used to. maybe the inflammation in a spot goes down about 30% but not the 80% i used to get overnight.
Elysia B.
16 reviews
Beauty Junkie Expert Level 1
This product makes monster pimples disappear almost over night. I recommend and for the price you can't go wrong, I have used the Clinique spot treatment and this one beats it by 100 miles I will be buying again.
Lauren K.
Taunton, MA
63 reviews
Beauty Junkie Expert Level 1
This is my favorite acne product. Just a few drops before bed and it clears up acne by the next morning ( or in a few days) it's not completely drying so I feel good about using it. I would definitely recommend to others who want to get rid of there acne!
Amy D.
Lansing , IL
268 reviews
Beauty Junkie Expert Level 4
Love this on spot acne treatment! It definitely helps with my acne! When it's an open pimple it stings a little but it works! Love that I can find at any drugstore! Also very affordable! A little goes a long way!
Hayley K.
175 reviews
Beauty Junkie Expert Level 3
This spot treatment works well in bringing my blemishes to the surface, and dries them out quickly. I have used this product since I was a teen, and have always found it to work very well. Will be buying again.
Karene L.
Orlando, FL
5 reviews
Does this product work for every skin type?
Patricia T.
Detroit, MI
1 review
Does this work well? I have used a few products over the years for my acne, and it just keeps coming back.
Denise G.
New London, CT
7 reviews
I have acne problems that have recently accur. Is this product good? Also is it okay to use for sensitive skin?
Sierra F.
1 review
How well does this fight off mild acne? And how quickly
Kelsey W.
Liberty Lake , WA
16 reviews
Looking for a quick spot treatment remedy for pimples. How long does this product need to stay on to take affect?

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