Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,717 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,723)
Q&A (493)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
annemarie v.
Ontario, CA
71 reviews
Beauty Junkie Expert Level 2
this will sometimes work soooo good and fast for me and sometimes take waaay longer. I'm giving it 4 stars rather than 3 because there were several instances where my pimple would clear overnight so i give it props.
Kylee F.
Franklin, TN
73 reviews
Beauty Junkie Expert Level 2
I have bought this product many times. It worked really well on acne spots. It cleared them up very fast. I would suggest other products to use with it to prevent acne from coming back. Other than that great product!
Rachel Y.
Riverside, CA
68 reviews
Beauty Junkie Expert Level 1
I use this stuff everyday, it's been a life-saver. When I have really bad breakouts, ill put this on and the next day it's already noticeably better. It's fast working and easy, and the little tube will last so long.
Shelbie R.
8 reviews
This product takes maybe two applications to see a noticeable difference. It doesn’t even dry out my (already naturally) dry skin. A little goes a long way, I expect the tube to last me all the way to it’s expiration date. I recommend for all skin types!
lauryn d.
Tempe, AZ
28 reviews
Beauty Junkie Expert Level 1
I've put this on spots I feel a pimple coming and it just shuts it down. It always works for me and helps me keep breakouts under control. I don't use it that often or a lot when I use it so it has lasted me a while.
paty R.
San diego, CA
54 reviews
Beauty Junkie Expert Level 1
I used this with the 3 other clean and clear it comes with. It really does work but it stung a bit maybe because I have sensitive skin but I could not use this my brother end up keeping it and I would say it did work
Maica C.
Lexington, KY
288 reviews
Beauty Junkie Expert Level 4
This is pretty amazing at spot treatment. I was using my friend's bottle and was extremely impressed. The best part is that it's so affordable and can be purchased basically anywhere. I will definitely be purchasing.
Sam H.
Vine Grove
95 reviews
Beauty Junkie Expert Level 2
This stuff will squash a pimple in no time. I love putting this on before bed. When you wake up, your pimple will be at least half the size if not gone (depending on how bad).
Ashley S.
Ona, WV
44 reviews
Beauty Junkie Expert Level 3
This is a pretty great product. I use it frequently and keep coming back, so obviously I does it’s job. I use it as spot treatments as soon as a pimple appears. This product doesn’t dry out my skin like others do.
Elizabeth F.
Boston, MA
15 reviews
This little silver tube is my go-to for when I can feel a spot starting to form on my face. The salicylic acid dries any pimples right up, even before they come to a head usually. I've been using this for years, and I'll be using it for years to come.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

Sign up to join our community!

Influenster Cashback
We recorded your visit.
Clean & Clear® Advantage® Acne Spot Treatment

Amazon was opened in another window. If you made a purchase Cash Back will be automatically added to your Ebates account tomorrow.

Please confirm your email.
If you have an existing Ebates account, make sure to enter your Ebates email

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.