Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #10 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,756)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Amber D.
Fort Worth, TX
12 reviews
This product I love but then I don't. The product works well but you do have to use a little amount on your face. A pea size amount. If you use a little too much it does dry your skin and leave it sensitive but it does work well if you use the right amount
Amanda J.
13 reviews
This is an ok product. The price is reasonable but I think it only sort of works.  After a few days of use it does seem to help with my blemishes but they would have cleared up on their own in a few more days anyways.  I wouldn't really recommend this unless you have minor blemishes and aren't in a huge hurry for them to go away
Meghan F.
48 reviews
Beauty Junkie Expert Level 1
I use this whenever a pimple pops up. I think it does a good job of drying blemishes out. To me, I also think it helps make them go away much quicker than they would if I just left them alone. Plus the price is great for something so effective.
Elizabeth S.
11 reviews
This is a really strong spot treatment if you're looking for one to help aid in diminishing cystic acne. I've been using it for a while and I can see a visible difference in the redness and size after just using it overnight. It's a really great product 
Cheyenne M.
9 reviews
Beauty Junkie Expert Level 1
I have very troubled skin and I struggle with acne. This product was very gentle on my sensitive skin and it has worked wonders for my skin. I put it on 1-3 times a week and when I wake up my acne is barely there. I'd definitely repurchase this product.
Candy M.
Clearwater , FL
50 reviews
Beauty Junkie Expert Level 1
I don't get pimples very often but this product is great for the once in a whiles. This it was very effective and I'd use it again if needed. Spot treatment at it's best. It's easy to find at CVS and priced well. It really works and helps with pimples.
Kelly H.
44 reviews
Beauty Junkie Expert Level 1
I use this product whenever I find spots or pimples on my face. Is is great and does not overly dry out the skin. It is a great bang for your buck and I would definitely recommend this product to all. I stick with this product because I like it so much.
Caeleigh F.
80 reviews
Beauty Junkie Expert Level 1
It doesn’t work at all all it does is just flake that area around it in dry out your skin it doesn’t really make your pimple go away does it make marks go away and in fact makes them more noticeable when you put on make up over it or anything it’s just not a good product especially not for the price
whitegirlroadtrip ..
Mount Clemens, MI
59 reviews
Beauty Junkie Expert Level 3
This is my immediate go to product. If I feel a zit coming on, if I have a red mark, I use this and it goes away almost overnight! It's a great value - you get a good amount of product that lasts you so long and it is such a reasonable price. I love it!
Alex R.
192 reviews
Beauty Junkie Expert Level 2
This spot treatment worked a lot better than other ones that I have tried. It also didn’t dry out my skin as others would. There also wouldn’t be really any redness after applying it.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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