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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,314 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10314)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Aushlin L.
Hoyt, KS
63 reviews
Beauty Junkie Expert Level 1
This really helps get rid of redness of acne within 12 hours, well at least on my skin! Works quickly, doesn't dry my skin out, and pretty effective in clearing up those lone pimples. I would recommend this to others!
Rachel I.
Layton, UT
6 reviews
Beauty Junkie Expert Level 2
I like this product. I think it does a little to help my acne and breakouts. But I definitely noticed that it isn't curing it or working super quickly. A little disappointing. I would have hoped it was more effective.
Betsy J.
19 reviews
This stuff is excellent for the regular acne I have. It doesn't do as well on the cysts and other larger bumps, but for mild-to-medium breakouts, this is my go-to!
Makeia C.
Santa Monica, CA
13 reviews
Beauty Junkie Expert Level 1
Always my go to for spot treatment when I see a zit coming my way. I'll apply twice a day for that time and usually clears up pretty quickly. Light, non greasy and easy to keep... takes up little space in a makeup bag
Sarah T.
Gainesville, FL
60 reviews
Beauty Junkie Expert Level 2
This product can be extremely drying and can cause dry patches. While it doesn’t work as quickly as some other products, it will eventually help reduce the size of a blemish and the price point is fair for the product.
Grace S.
27 reviews
Beauty Junkie Expert Level 1
This is great for the times when a pimple pops up. It kills the pimple in a couple days. It's easy to find, and Great for people who have acne breakouts. It's also small inconvenient for travel. Overall I recommend it
Alyssa R.
Fife , WA
7 reviews
Great for spot treatments on big pimples or small pimples. It is very drying so use it sparingly. Also it it’s kind of like a clear glue so it peels or rubs off it you put too much. I only use it at night. It doesn’t work well under makeup.
Veronica D.
50 reviews
Beauty Junkie Expert Level 1
Eh. Heard rave reviews about this stuff, but it only works on large obscenities. Don't go overboard on this stuff- it will dry the hell out of your skin. Don't use it anymore, but it is a great overnight emergency fix.
Romina S.
Saratoga, CA
19 reviews
Beauty Junkie Expert Level 1
I used this for a few months but my skin is so sensitive, and this product made my face turn red. I bet it works, i have friend that ude this and works pretty good, but if you have sensitive skin, this is not for you.
Bellatrix S.
Sacramento, CA
68 reviews
Good for after popping pimples but not as great for regular acne. Small amount and bad pricing for the size but overall an okay product. I have bad breakouts and I use it occasionally. I recommend the Persa-Gel instead
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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