Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,456)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Staci K.
8 reviews
Its a great acne remover. Good for pesky little pimples that pop up at the worst times. Good size for travel,  stores easily in purse or make up bag, backpack etc. Easy to apply. Clears pimples fast, the best fast acting pimple remover. Only down fall so little package, and price range is thrust the roof. 
Jenna W.
Fayetteville, AR
18 reviews
This Acne Spot Treatment is a great alternative to prescription acne treatments. While it is not very effective for cystic acne, it does a wonderful job of quickly eliminating regular pimples (those with white heads). I highly recommend this product for individuals looking to treat acne without breaking the bank.
Anna J.
7 reviews
Not a big fan. I say this because I used this product for weeks and it didn’t work and it was highly disappointing. It made my skin red and irritated while still continuing to have acne. Waste of my money and I wouldn’t buy it again. That is from my personal experience so it can be different for everyone. 
Montserrat C.
38 reviews
Beauty Junkie Expert Level 1
I bought this because a LOT a people on instagram were talking about this and I thought I'd give it a try. I had really bad acne when I first started using this and I would use it on the biggest and redness breakouts I had. I would use it daily and not see a difference at all. I thought to myself it was probably cause my acne was so bad, so I just continued buying it thinking that it was working but I just couldn't tell. By my third tube I had just started using the Keeva Organics acne cream (don't remember the official name sorry) and saw results almost instantly. I figured that this spot treatment didn't work for me 😕😕 So yeah, I just finished the tube I had and haven't bought it since.
Clean & Clear® Advantage® Acne Spot Treatment
Kristen M.
62 reviews
Beauty Junkie Expert Level 2
This product has been my go to acne spot treatment for years now. It does exactly what it says. Yes some experience dryness. It’s drying up all the zit funk. If I feel a pimple I take a q-tio and apply it to the area. Do not cross contaminate. Do not use the q tip or finger to rub this on the zit then touch the product tip or another part of your face. You’re spreading the bateria that way. Make sure to use qtip and rub around the whole pimple. You’ll see reduced redness or a big white head... you’ll need to pop or stick a safety pin in  Clean & Clear® Advantage® Acne Spot Treatment
Desiree G.
Springtown, TX
14 reviews
This product worked so well! I just used a tiny amount on each spot and by the next day they were already looking better. The price was great, packaging was easy to open. It wouldn't say the product is harsh but I wouldn't say it was gentle either. I would 10/10 recommend this product to others!
Izzy M.
Colorado Springs
6 reviews
The product seemed to take forever to get working, and was dissapoingting it just seemed to dry out my skin and didn’t do much for me, it was too harsh for my dry skin. It could be better for someone else and would be worth the money. 
Clean & Clear® Advantage® Acne Spot Treatment
Trisha B.
Salt lake city
1 review
I love this stuff. When I start to break out I put this on each little sport after washing my face. And two days tops its gone. I swear by this stuff and recommend any one to use it if they haven't yet. Try  Clean & Clear® Advantage® Acne Spot Treatment  you will love it! 
Emily S.
18 reviews
Purchased at: Walmart
This product does well with spot treating acne and does not dry out the skin. I use it in the morning before applying my makeup and every night after washing my face and it helps keep my acne under control! This is a great product for stubborn zits that pop up that you want to go away fast!
Sasha B.
11 reviews
I’ve been using this product for years. It’s not mind blowing, but it does what it’s supposed to. It dries out acne. It’s not incredibly powerful, but it’s strong enough to do what it needs to. Again, it doesn’t perform overnight miracles, but it is effective. Since I’ve been using it for years, I will probably continue to buy it unless a miracle product finds its way into my dressing table. 
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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