Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,523 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10523)
Q&A (464)
Media (121)
Buy on Amazon
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Angelica M.
Bolivia, NC
43 reviews
This product didn’t work for me. But it worked for a lot of my friends. I guess it’s about what works for you nothing everything everyone else uses will always work for your skin
Amber M.
Fullerton, CA
53 reviews
Beauty Junkie Expert Level 2
I have been using this since high school. It's such a great product at night a little dab on problem areas or during the day under your make up kills the redness instantly. I couldn't love with out it
amanda s.
33 reviews
Beauty Junkie Expert Level 1
I used this product for year and I love it. I've seen great results of reducing redness and quickening the healing process. Its most affective if you catch the breakout early. But it can sting if you apply it on a recently popped zit or pimple.
Jess N.
49 reviews
Beauty Junkie Expert Level 2
I have tried this product over night and it did not personally work for me. Even after a couple of tries. It was not harsh on the skin but did not show any improvement. Wouldn’t recommend.
Julia P.
Toronto, ON
69 reviews
Beauty Junkie Expert Level 1
This product is insane! Literally applied it to a breakout 30 minutes ago after washing my face and I can already see a huge improvement. I bought this because of its Influenster reviews and I’m so impressed. Definitely my new go-to acne product!
Kendall S.
14 reviews
This spot treatment really works. It stings when you put it on, but that’s usually when I can tell that it’s working. I got it from Target. It’s pretty expensive for how much product you get, but a little bit goes a long way. I would repurchase.
Bethany J.
Cincinnati, OH
991 reviews
Beauty Junkie Expert Level 5
I normally get big zits on my head and nothing budges them not even popping them or using expensive stuff helps them. This dries your skin out but it works without using it more than two times
Masey Y.
Lancaster, OH
78 reviews
Beauty Junkie Expert Level 2
This product does not lie. You put it on your acne spots, go to sleep, wake up and they're all gone. I genuinely love this product. The only downside is after you wash it off in the morning, use a very good moisturizer because it is very drying.
Bethany R.
69 reviews
Beauty Junkie Expert Level 1
Put in my skin at night with a thin layer by morning most if not all of the blemish was gone. Used all of the face. If used in the morning it left a film over where I used it and didn’t sit well with makeup
Krista Z.
Darien, IL
120 reviews
Beauty Junkie Expert Level 2
Leaves a weird film on your skin that pills up on your face when you apply makeup.  Definitely would not reccomend.  Also, burned when I used it and often left my skin red for a very long time.  I have used products with the same medication concentration before and never had the same problem.  
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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