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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,283 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10283)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Courtney N.
40 reviews
Beauty Junkie Expert Level 1
I swear by this stuff!!! Great for pesky pimples that pop up overnight. I recommend this to all my friends, male and female. Good price for the product. One tube lasts me about a year.
Laura Kay S.
Alexandria, VA
188 reviews
Beauty Junkie Expert Level 3
Great acne treatment if you are experiencing dry or oily skin combinations! It lasts me for a little over a month and does the job without causing sensitivity or irritation. It's great for problem pimples that you don't have much time to get rid of. 
Megan G.
91 reviews
Beauty Junkie Expert Level 1
Not in love with this product. Tried several times and have seen no results. A bit pricey as well. The clear gel is easy to apply. I would not recommend this product to others as I did not have a great experience with it.
Victoria F.
Middletown, CT
28 reviews
Beauty Junkie Expert Level 1
One of the first acne spots treatments I’ve used since 2006. I️ still use it and it’s awesome. Compared to other spot treatments it’s a little more medical smelling but does the job. I️ya good for my skin but I️ wouldn’t recommend for people with dry skin.
Morgan G.
13 reviews
I used this for years back in high school when I would have breakouts. I would cleanse my face and then apply this to problem areas and the next morning they were totally down in size and drying out. It is drying but thats what gets the suckers gone! 
Shelley L.
Pamplico, SC
32 reviews
Beauty Junkie Expert Level 1
This works really well for the most part. My only thing is it doesn't work that great on large pimples or deep seeded ones. Or it didn't for me, at least, and we are all different! What works for one may not work for all. Other than that, i love using this because it gets rid of smaller zits super fast!
Katelyn D.
Allen, TX
40 reviews
Beauty Junkie Expert Level 1
This stuff really works. I️ like to put it on at night and in the morning I️ wake up with my inflammation gone down and my pimples dried up. I️ love that it’s clear so I️ can wear it under makeup. It dries the spot without drying up the rest of your skin.
Elizabeth H.
12 reviews
I swear by Clean & Clear's face wash and Acne Spot Treatment. It comes in incredibly handy for any breakouts that come my way, and does a good job of either stopping breakouts or reducing their recovery time without being too drying on the skin. 
Eliana C.
Gordonsville, TN
89 reviews
Beauty Junkie Expert Level 2
I don't think this product works very great, but maybe that's just my skin. Whenever I use it I feel like it's so thick that I might be making the breakouts worse. Never really works for me
Sofia C.
caldwell idaho
120 reviews
Beauty Junkie Expert Level 2
I use this when I have a pimple , I put it on the irritated pimple and I do see that the pimple slowly reduces and shrinks , this product is really good and I recommend it for anyone !
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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