Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,752 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,757)
Q&A (505)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Kat L.
House Springs
10 reviews
This is my go to, “I have a pimple and I need it gone treatment.” It’s a great product and I like the packaging too. It fits nicely in your purse and isn’t too harsh on my skin. So yes I would definitely recommend this to a friend and but this product again.
Mali H.
29 reviews
Beauty Junkie Expert Level 1
I don't see much improvement or clearness of my skin from using this product. I bought it a few months ago and use it occasionally but I won't be using it again. It stings a bit after application and trying to wash it off is awful. If you don't wash it off it peels and makes your skin look flakey. If you do wash it off it takes a while and it can get in your eyes. This isn't a good treatment of acne and I don't recommend it to anyone.
Carly B.
91 reviews
Beauty Junkie Expert Level 2
This is my absolute favorite acne spot treatment. It works well and it works fast and the price is GREAT! I consistently repurchase this item and recommend it to my friends and family all the time. This is my holy grail
Kira A.
88 reviews
Beauty Junkie Expert Level 1
This product is great for stubborn acne. I use it after I clean my face and moisturize. The only way it has dried my skin is if I use it a crazy amount. It works wonders on my pimples and makes them disappear so quickly
Kaitlynn V.
33 reviews
Love this spot treatment! I cannot find it in my local drug stores anymore so that’s a bummer. I really enjoyed this product and would carry it with me as often as possible. I always felt like it worked quickly and got the job done
Melissa W.
Aspen, CO
99 reviews
Beauty Junkie Expert Level 2
This has been my go to spot treatment since I was in middle school-so well over 15 years! I use it anytime a pimple comes up and it helps overnight every time! I buy mine at Target or any drugstore. Cheap and effective!
Courtney C.
waltham, MA
50 reviews
Beauty Junkie Expert Level 1
This spot treatment works wonder on my face! I get a couple pimples that time of the month. And this in my face before bed and the pimple is usually gone or at least the redness is gone so my makeup can cover it easier.
Alicia R.
Mount Vernon
14 reviews
Works ok. I feel like as soon as I stopped using it due to being busy the acne came back right away. If you want to get rid of acne soon I don’t recommend this product. This product has to be used a lot to take affect.
Morgan K.
Des Moines, IA
132 reviews
This spot treatment took a few days for my breakouts to start clearing/calming down. The first time I used it, my blemishes were noticeably less red/inflamed, however there was a dark spot left on my skin after it dried up after a few days. This may be typical for spot treatments, as this is the first spot treatment I’ve used. There was no stinging or harsh smell at all. It did it’s job and I will use this whenever I have an out of control blemish.
Megan A.
Toronto, OH
80 reviews
Beauty Junkie Expert Level 1
This product does wonders! It gets rid of acne so quickly! I love applying this after I pop a pimple so the product can really get in there and dry it up and that usually seems to work! I highly recommend this product!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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