Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,755 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,798)
Q&A (507)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Emily H.
Denver, CO
7 reviews
Uh yes hi life saver. This stuff is my go to for a breakout. I have a drying mask I apply, then pop this on at night. If you use it too often, it will dry out the area you're applying to but that's a given with the acid in it. But it's certainly worth it especially at this price.
Devin B.
Tulsa, OK
70 reviews
Beauty Junkie Expert Level 1
This wasn’t effective for me. It also doesn’t absorb but rather left a weird film that would ball up if you touched your face after you think it’s absorbed. It seems like it’s absorbed but it has not.
Heather W.
South Haven, MI
3 reviews
Beauty Junkie Expert Level 1
I dont have break outs all the time but when i do this is my go to spot treatment. On top of that its a fantastic price point, at my local store its $6.59. The packaging is really helpful with applying the product to a specific spot. I usually apply at night after washing my face. 
Mary Grace D.
Houston, TX
66 reviews
THIS IS A LIFE SAVER! This stuff is gentle without over drying. I have used this since I was a teen and now I'm 30 and still use it! This will zap my zit right away and I will always repurchase this as long as they sell.
Morgan R.
27 reviews
I LIVE by this spot treatment! If I have acne pop up over night, I can put a small amount on the spots and notice them go down throughout the day. It’s kinda pricey for a small package but WELL worth spending the extra few bucks on.
Georgiana M.
190 reviews
Beauty Junkie Expert Level 2
It works. Still, two stars off because my tea tree oil works just as well, and does that dry out my skin causing flakes (on my oily skin!). I hate that some acne treatments will dehydrate my skin so the point of flaking, yet my skin is naturally oily, and it'll make it go into overdrive.

Not cool. Still looking for a better product.
Melissa B.
Arvada, CO
151 reviews
Beauty Junkie Expert Level 5
When I need quick treatment of a really bad pimple I use this to rush it away haha it actually does it's job which is nice for it's price. I bought it at Target and it was my first time using it. I would definitely buy this again if I needed it. I would definitely recommend it to others.
Fawzia E.
239 reviews
Beauty Junkie Expert Level 3
This is my go to spot treatment! Usually I don't like putting a lot of things on my face unless they are natural but this has cure my pimple every time. It reduces the size and redness of it overnight!
Chelsey C.
88 reviews
Beauty Junkie Expert Level 1
The worst reaction ever ! I didn't think I had sensitive skin but after using this and the other recommend products to use together my face my fire red and broke out in tiny red dots ! Not for me !!
Hope V.
179 reviews
Beauty Junkie Expert Level 3
This spot treatment is terrible. It made all of my pimples bigger, they wouldn't go away, and more breakouts just kept happening. Salicylic acid is a really really harsh ingredient on sensitive and acne prone skin and I do not recommend using this or any other product that has it
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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