Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #10 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars16%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,792 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,801)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Mandi H.
26 reviews
Beauty Junkie Expert Level 1
I seriously recommend this stuff to everyone! I discovered the product in high school, and now it's my go-to whenever I have a blemish. I don't have to use it regularly, but it's great for quickly clearing up the occasional blemish. It's also gentle, never harsh, and (because I don't use it too often), it seems to last a while despite the small tube it comes in!
🌻Breanna P.
30 reviews
Beauty Junkie Expert Level 1
I LOVE LOVE LOVE this product. I don’t stay anywhere without it. I use it three times daily and it really helps. I use this more than face wash and it has so far worked the best. I absolutely love it. I buy it all the time. Very affordable. Highly recommend!
Toria H.
Orlando, FL
66 reviews
Beauty Junkie Expert Level 2
This product saves me multiple times! Overall my face is pretty clear, so when I get a blemish it really stands out. I use this and within hours I notice the blemish begins the process of fading away. Within about 2 days it's usually gone. I have been using this since middle school. I can make your skin over dry with excessive use but other than that I love it.
Melina J.
122 reviews
Beauty Junkie Expert Level 2
If anyone suffers from acne and need a quick treatment, THIS IS FOR YOU. I bought this in middle school and still have it on hand if something has happened to my face the night before or day of an event. It works really fast as if I never had any acne. Obsessed with this. I have it stocked up under my bathroom cabinet. I won't be running out anytime soon. 
Stephanie B.
7 reviews
This acne treatment is amazing ! It really works and smells great! It goes on very smooth and doesn’t require much; therefore it will last awhile! This tube is well worth the money! I also like that it didn’t leave a film on my face; it still felt very smooth and soft! I highly recommend this product !
Taylor F.
North Providence
18 reviews
I don't have many blemishes but when I do I put a little bit on the pimple, after my skincare routine and a spot treatment with Glamglow gravity mud, and go to sleep. I wake up and the pimple is practically gone! Its inexpensive and gets the job done. The only issue is if you use to much it can be drying because of the alcohol in it but other than that its great!
Nicolette P.
8 reviews
This is my go-to spot treatment and I can’t live without it! Whenever I have any sort of breakout I put this on and it’s gone within a few days (depending on how bad). I swear by this product and have made friends and family purchase it for themselves. 
Lauren C.
36 reviews
Beauty Junkie Expert Level 1
My absolute go-to product when it comes to quickly zapping pimples! Works quickly and effectively to banish any blemishes! I prefer this product because it is clear, so I can put it on at night, or in the morning before I go out in public, and no one can tell I have it on! This has been one of my staple products for the past few years, and I absolutely love it!
Abeni S.
23 reviews
Beauty Junkie Expert Level 1
I love this stuff for real. It works so good in clearing up acne, after you've popped it, and before acne even comes up. I have 1 or 2 pimples a month so i really don't struggle with acne but if you do i would highly recommend this spot treatment to you.
Megan C.
54 reviews
Beauty Junkie Expert Level 1
This is a great drug store product. I don't get acne much but I do feel like this product really zaps a zit when it comes. The clear formula is great so that it is not obvious if you are in public or if you want to put makeup over it. Great price as well.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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