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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,303 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10303)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Britny B.
10 reviews
At first I bought this for my boyfriend, but I started to notice it working for him so I thought I'd give it a shot too. It works pretty good, I notice a difference in my spots by the morning. It's pretty gentle but I do notice it gets a little drying around the spot I applied it to, but that doesn't bother me much. It's good for the price too, so I don't have many complaints.
Mariant C.
Doral, FL
55 reviews
Beauty Junkie Expert Level 3
Perfect for sensitive skin.
I have been using this product for about a week, I use it at night after wiping my face with its non-transparent bar. This product is very nice, I do not have very sensitive skin and I'm not a fan of using localized treatments because of that, but this treatment is very gentle on the skin and reduces the redness of the acne scars and acne that I have .
jaimie l.
79 reviews
Beauty Junkie Expert Level 2
this was my go to spot treatment years ago. id use it when i felt a bump coming in the night before and id work really well. id also use it when the pimple surfaced but over the years i find it to be much less effective. im not sure if its my skin type now but it almost burns
Kat V.
Rochester, NY
13 reviews
Beauty Junkie Expert Level 1
This product sometimes works for me and sometimes doesn’t. When it does work, it works great. I can feel the product stinging my acne which to me is a great sign that it’s working. When it doesn’t work, however, it sometimes leaves red spots on my skin. It’s definitely worth a try, but may not work for everyone.
Beth M.
16 reviews
Beauty Junkie Expert Level 1
I purchased this product hoping to help with the random acne breakouts that I have.  At first I didn't notice any issues, but the more I used it the more I noticed that my skin would have bad reactions to it.  I also noticed that it had some ingredients that would cause bleach-like spots on my pillow cases.  I will not be purchasing this product again. 
Ali R.
Lake Worth, FL
14 reviews
Beauty Junkie Expert Level 1
I don't have bad acne, but I always have problem spots.  I never use acne fighting face wash, but spot treatments are my go-to.  I have used many spot treatments but after trying Clean & Clear, I have stuck with this product!  Totally recommend to others.  I gave this 3 stars because it doesn't work as fast as other spot treatments, but it doesn't dry out my face as much either.
Sara T.
Covina, CA
24 reviews
I've been using this stuff for at least a decade and a half and I love it! I have sensitive skin, but using this as a spot treatment isn't a problem. When I have a blemish, I generally put this stuff on once a day, at most twice a day. While the blemish doesn't disappear immediately, this product prevents the blemish from turning into a full blown zit, which is a win for me.
Kiersten C.
7 reviews
I’ve had this for a long time and it’s sort of a last resort kind of thing. I always make sure I was my face and if I see a blemish coming in then I’ll put a dab of this on it! Sometimes it works and sometimes it doesn’t, it just depends. I’d say it’s worth the price
Carly W.
42 reviews
Beauty Junkie Expert Level 1
Clean and Clear doesn’t really work out for me. When I used this the last time my face broke out and was swollen and read. Probably something to do with the ingredients that i’m allergic to. Just make sure you read ingredients before but that’s totally up to you if you want to try this out!
Cayla R.
Norwood, PA
32 reviews
Beauty Junkie Expert Level 1
Clean & Clear® Advantage® Acne Spot Treatment - I've bought this product twice. It is really effective and it dries out the area you apply to. One thing I'd be caution of is that it's excessively drying so if you have dry sensitive skin like I do avoid the eyes and your most sensitive areas. Other than that it's the next best thing to Glam Glow's spot treatment mask.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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