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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,305 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10305)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Karen Y.
31 reviews
Beauty Junkie Expert Level 1
not much noticeable results the first few uses, but effects start showing after a while. if i feel a bump growing or soreness, i pile this stuff on the spot and wake up the next day with no soreness and a reduction in the size of the bump. an affordable and effective buy!
Hailey D.
Midway Park, NC
158 reviews
Beauty Junkie Expert Level 2
Can’t even lie I hands down LOVE this stuff. It’s kinda pricey for this little tube but this magic goes a loooonnng way! It literally is a spot treatment that works overnight. You can get it at any drugstore or cosmetic store and you’ll fall in love with a spot free face.
Alexis T.
196 reviews
Seriously the best “spot treatment” ever!! I will put some of this on my acne spots and in the morning they are visable smaller or even gone! The price isn’t bad at all from what I can remember! I bought this for my little sister and she loves it as well. I would highly recommend this product!! Worth every penny
Jarielly S.
122 reviews
Beauty Junkie Expert Level 3
I used to use this when I was younger and holy cow how it works !!!
I used to get pimples allllll the time and my mother bought me this and this was the only product I used on my face ! It was my holy grail . I don't remember much on this like the smell or how it felt but I do recommend this if you have acne scars or any pimples just put it on the problematic areas and let it sit !!!
Emily E.
264 reviews
Beauty Junkie Expert Level 3
I had a few friends who liked this stuff, but I don't think it worked for me. Pretty disappointing. I am willing to try it again.
I think I need something to help more now, than I did a few years ago.  Some acne products work best on an open blemish. and helps it heal a bit quicker ( Maybe?) after.... Maybe I misused it? I don't know, could be one of those 'cone things... like Dimethicone or something??

Esmeralda C.
Miami, FL
54 reviews
Beauty Junkie Expert Level 1
I was looking for a treatment that would remove my acne scars without having to pay to much money.I saw this product and decided to get it due to it's great price and due to my great experience with clean and clear . I used as soon as i cleaned as I washed my face and it was amazing it was gone in 2 weeks and if it is not gone the product at least's erase some of the imperfection
Shannon J.
Orlando, FL
198 reviews
Beauty Junkie Expert Level 4
I got it from Walmart for a little less than $6. It seemed to work very well at first. I've always had great skin, but recently I started having outbreaks on my forehead and checks. I noticed the difference minutes after use and after a few days the blemish would be gone. Well I've been using it for a few months now and now it doesn't seem to work at all. A little disappointed.
Lauren M.
18 reviews
Beauty Junkie Expert Level 1
This product is all right. I use it on my acne blemishes and it keeps them at bay. Although, I don’t see immediate results. Also, the product stings when it is used on open pores or blemishes. It is just another drugstore acne spot treatment, nothing special about it.
Britny B.
10 reviews
At first I bought this for my boyfriend, but I started to notice it working for him so I thought I'd give it a shot too. It works pretty good, I notice a difference in my spots by the morning. It's pretty gentle but I do notice it gets a little drying around the spot I applied it to, but that doesn't bother me much. It's good for the price too, so I don't have many complaints.
jaimie l.
79 reviews
Beauty Junkie Expert Level 2
this was my go to spot treatment years ago. id use it when i felt a bump coming in the night before and id work really well. id also use it when the pimple surfaced but over the years i find it to be much less effective. im not sure if its my skin type now but it almost burns
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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