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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,294 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10294)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Mia H.
Birmingham , AL
51 reviews
Beauty Junkie Expert Level 2
Use this stuff whenever I have a stubborn pimple pop up, does the job! I have never had it dry out my face or peel skin off like others have and I have combination skin and will usually dot my pimples first then just use whatever is left on my hands to rub all over my face!
Michelle M.
Tampa, FL
89 reviews
Beauty Junkie Expert Level 2
Love Clean and Clear Advantage Acne Spot Treatment!!!! This gel goes on clear and usually clears up breakouts overnight. Don't be tempted to pick at your skin because this stuff burns like crazy on any open sores!I've been using this gel for two years now and will not switch to any other brand. Can't beat the price. Anything that costs $10 and has amazing results like this is well worth the cash!
Faiza M.
Yonkers, NY
52 reviews
Beauty Junkie Expert Level 3
Definitely a fan of this product and it's a great spot treatment. Beware though - it will cause dryness! I actually do not use it over night because I find that the next day that area of my skin is too dry. What I like to do is apply this after my primer and before my makeup routine. It actually helps the makeup from irritating the already existing acne. A must have in everyone's cabinet.
kaila w.
Glendale, AZ
71 reviews
Beauty Junkie Expert Level 1
I didn't use this for very long but when I did I feel like it worked very well. It did not excessively dry out my skin and it seemed nice. I did not repurchase it when I ran out though because it was not necessarily life changing, but I do feel like it works decently. 
Abbey P.
Athens, GA
55 reviews
Beauty Junkie Expert Level 3
I liked this product but sometimes it seemed to decrease redness and overall inflammation while increasing the overall healing time until the blemish was actually gone. I’ve gotten this product several times because it works in a pinch but isn’t a go-to for acne care for me.
Shannon F.
134 reviews
Beauty Junkie Expert Level 1
I use this every night and sometimes I'll see a pimple vanish by the morning! It's a great formula and inexpensive. The only time I've seen it make my skin a bit oily is if I use it more than once a day, but I believe that's just my skin type. It's the best way I've found to treat those pop-up pimples fast. Just a tiny dab on each problem area is all you need, so it lasts a long time too.
Karen Y.
31 reviews
Beauty Junkie Expert Level 1
not much noticeable results the first few uses, but effects start showing after a while. if i feel a bump growing or soreness, i pile this stuff on the spot and wake up the next day with no soreness and a reduction in the size of the bump. an affordable and effective buy!
Grace H.
24 reviews
Beauty Junkie Expert Level 1
This product worked well when I used it on a pimple forming under the skin. It’s affordable and if you know salicylic acids works for your skin, id recommend trying it out. Only four stars because I think my skin got used to the acid concentration and wasn’t as effective, but I could be wrong!
Alexis T.
196 reviews
Seriously the best “spot treatment” ever!! I will put some of this on my acne spots and in the morning they are visable smaller or even gone! The price isn’t bad at all from what I can remember! I bought this for my little sister and she loves it as well. I would highly recommend this product!! Worth every penny
Jarielly S.
122 reviews
Beauty Junkie Expert Level 3
I used to use this when I was younger and holy cow how it works !!!
I used to get pimples allllll the time and my mother bought me this and this was the only product I used on my face ! It was my holy grail . I don't remember much on this like the smell or how it felt but I do recommend this if you have acne scars or any pimples just put it on the problematic areas and let it sit !!!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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