Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #8 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,751 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10,756)
Q&A (504)
Media (125)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Grace H.
24 reviews
Beauty Junkie Expert Level 1
This product worked well when I used it on a pimple forming under the skin. It’s affordable and if you know salicylic acids works for your skin, id recommend trying it out. Only four stars because I think my skin got used to the acid concentration and wasn’t as effective, but I could be wrong!
Ellen N.
111 reviews
Beauty Junkie Expert Level 2
I only gave 3 stars which I don't like to do, but only gave 3 stars as it didn't not work for me, and with acne products everyone is different, I have cystic acne with some little normal pimples, the older I get the oiler my skin gets and the worse my cystic acne gets, so with that being said this product did not make a difference on my skin, did not make it worse nor better, keep in mind with acne products I do give it 90 days minimum before giving review, if you have not tried this product I would at least give it a try as it may work for you.
Alexis T.
203 reviews
Seriously the best “spot treatment” ever!! I will put some of this on my acne spots and in the morning they are visable smaller or even gone! The price isn’t bad at all from what I can remember! I bought this for my little sister and she loves it as well. I would highly recommend this product!! Worth every penny
Hailey D.
Midway Park, NC
178 reviews
Beauty Junkie Expert Level 2
Can’t even lie I hands down LOVE this stuff. It’s kinda pricey for this little tube but this magic goes a loooonnng way! It literally is a spot treatment that works overnight. You can get it at any drugstore or cosmetic store and you’ll fall in love with a spot free face.
Karen Y.
31 reviews
Beauty Junkie Expert Level 1
not much noticeable results the first few uses, but effects start showing after a while. if i feel a bump growing or soreness, i pile this stuff on the spot and wake up the next day with no soreness and a reduction in the size of the bump. an affordable and effective buy!
Jarielly S.
125 reviews
Beauty Junkie Expert Level 3
I used to use this when I was younger and holy cow how it works !!!
I used to get pimples allllll the time and my mother bought me this and this was the only product I used on my face ! It was my holy grail . I don't remember much on this like the smell or how it felt but I do recommend this if you have acne scars or any pimples just put it on the problematic areas and let it sit !!!
Dani F.
74 reviews
Beauty Junkie Expert Level 1
I really like this simple spot treatment for a salicylic acid treatment option. This stuff is great for little white heads in my nose. It’s gentle enough to treat my nose for a week at a time. With all acne medications, I only use it when I absolutely need to. Love it!
Esmeralda C.
Miami, FL
58 reviews
Beauty Junkie Expert Level 2
I was looking for a treatment that would remove my acne scars without having to pay to much money.I saw this product and decided to get it due to it's great price and due to my great experience with clean and clear . I used as soon as i cleaned as I washed my face and it was amazing it was gone in 2 weeks and if it is not gone the product at least's erase some of the imperfection
Mariant C.
Doral, FL
55 reviews
Beauty Junkie Expert Level 3
Perfect for sensitive skin.
I have been using this product for about a week, I use it at night after wiping my face with its non-transparent bar. This product is very nice, I do not have very sensitive skin and I'm not a fan of using localized treatments because of that, but this treatment is very gentle on the skin and reduces the redness of the acne scars and acne that I have .
Jennifer M.
Feeding Hills, MA
66 reviews
Beauty Junkie Expert Level 1
This tiny little tube works miracles for outbreaks. I picked it up at CVS while I was waiting for my prescription to be filled. Honestly, I only bought it because I had a coupon for it and I was killing time while waiting. I was extremely impressed when the day came that I developed a breakout. I used this gel on the acne and within a day or two, I noticed a dramatic difference.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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