Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #10 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars7%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,707)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Taylor M.
Destin, FL
24 reviews
This stuff is amazing! If I wake up with a small breakout, I immediately put this cream on. Once it’s on, the breakout will be gone in a matter of hours! It is incredible!
Jade Y.
35 reviews
Beauty Junkie Expert Level 1
Purchased at: Amazon
Best stuff! My brothers and I fight over tubes of this stuff because we all love it. Goes on clear so it can be worn in public and actually makes pimples disappear in days
Megan S.
Tampa, FL
81 reviews
Beauty Junkie Expert Level 1
This is my favorite drug store acne treatment. Works really fast and is very inexpensive. Will over dry if you put it all over though so definitely only a spot treatment.
Anika H.
Sterling Heights
130 reviews
Purchased at: Walmart
I’ve only used this couple of times and I’m not that much of an acne person. But when I do use it, its really good and it does the job. No patchyness not greasing nothing Really good
Stephanie S.
Horton, AL
87 reviews
Beauty Junkie Expert Level 1
One of the best products I’ve ever purchased for my skin. It starts clearing up blemishes overnight! It comes in a small tube but it will last a long time. Well worth it!
lisa d.
19 reviews
Beauty Junkie Expert Level 1
I have the definition of combination skin. In my t-zone, it's all oil, all the time. When you get to the areas surrounding my cheeks and chin, it's a desert. And, I have problem skin. Lovely to be me, right?

So I've been using this product forever, it's great in a pinch when you need to shrink a pimple for the following day, and cover it up with make-up, but it's not really a treatment per se. Recently, I've discovered the best way to actually use this product rather than the one stop solution I've been using it as for the past several years. didnt copy at all
Melinda K.
Sandy Hook, KY
113 reviews
Beauty Junkie Expert Level 2
Clean and clear has always helped me with acne. It's a very good product and it's very affordable. I love the way it heals my acne whenever I get the least little pimple.
👑Tommilee👑 T.
51 reviews
Beauty Junkie Expert Level 1
This spot treatment is great I like to use it at night after I wash my face and do a face mask then put this on my zits and leave it for like 10 minutes then wash it off.
Karla A.
36 reviews
Beauty Junkie Expert Level 1
It would make my pimples go away fairly quickly, it’s actually quite affordable and is great at meeting expectations, it always kept my skin of the affected areas soft and i would recommend a lot
Jacqueline K.
74 reviews
Beauty Junkie Expert Level 1
Definitely helps dry out acne and allow it to fade away but it also makes the skin around it very dry and irritated, hydration has to somehow happen at the same time
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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