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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,274 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10274)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Jessica N.
Proctorville , OH
74 reviews
Beauty Junkie Expert Level 1
I don’t have to use this a ton (I have AHEM mature skin,so I don’t break out often),but when I do have a pimple pop up this is my go to.I typically buy it at cvs,and it’s very inexpensive.It works wonders!I put this on after washing my face and the blemish is either drastically reduced or totally gone by morning.I will continue to use this as needed.
Sabrina C.
38 reviews
Beauty Junkie Expert Level 1
I started 2 use this product when it first came out. It's now a staple for me. For those who are considering getting this to treat their everyday acne, this is not the product for you. This is meant for the occassional pimple. That's why it's called a Spot Treatment & comes in such a small tube. If you use this everyday, your skin will quickly get use to it, and render it un-effective.
Christina S.
Poughkeepsie, NY
34 reviews
Beauty Junkie Expert Level 1
My acne story didn't start until this past year.  I did'nt struggle with it until I turned 23 so I am not familiar with acne product.  What I do know is this product works.  For the cheap price CC spot treatment will get rid of problemzits and blemishes over night.  After I wash my face I apply the tratment on problem zits.  It does dry the area, but not in a harsh way.  There are chemicals in it so it burns a little, which is to be expected.  
Liz R.
Philadelphia, PA
48 reviews
This is always in my medicine cabinet! I have oily skin and the salicylic treatment is the only spot treatment that my derm has approved for me that isn't prescribed. I trust this stuff. It NEVER makes my break outs worse and it almost always fixes a spot after one or two applications. My boyfriend also uses it from time to time. This is a must have!
Stacey O.
6 reviews
This product is really overhyped. I used this multiple times as a spot treatment and each time it leaves my skin very dry and flaky. Also it did not work to reduce the size of any of the pimples or even get rid of them. It’s definitely harsh on the skin and I do not recommend it for sensitive skin.
Samantha M.
62 reviews
Beauty Junkie Expert Level 1
This product is the best acne buster around! I suffer from cystic acne and this clears pimples in record-breaking time. I have sensitive skin, so I can’t use this daily, but compared to other products it’s minimally irritating and highly effective. Used in conjunction with a great moisturizer and only every other night, the results are amazing.
Lyndsey P.
Everett, WA
66 reviews
Beauty Junkie Expert Level 1
This works well on its own, you don't have to use the face wash and toner, or exfoliant for this to be effective.  I use it one some of my worst acne and find that within 24 hours there is usually some relief.  When I first started to use it, it would relieve redness, it doesn't do that as much anymore, but does relieve swelling.  It seems the efficacy of this product would be at a higher percent if they increased some of the percentages of the ingredients used. 
Taryn M.
81 reviews
Beauty Junkie Expert Level 2
I used this product in middle school and my first two years of high school. I gravitated towards this due to the price point and balling on a budget. 

This worked wonders for me for about two years. Then the results slowly started to dissipate. What I've found over the years with acne spot treatment products is I cannot use them daily or my skin becomes immune to them and their ingredients. When the product was giving me results it was great. The consistency was gel like, the smell was very strong. If I put this on my nose it would burn my eyes. But I find thats the case with most acne products so I won't bash the product over it.
Grace S.
Huntley, IL
92 reviews
Beauty Junkie Expert Level 2
I use this product every night. I get out of the shower, moisturize my face and then apply this to any pimples I have. I see results the next morning! I do not breakout very often but when I do this is my go to product. I would not recommend this product to anyone who had super dry skin because it does tend to dry your skin out a little bit.
Zaya W.
Louisville, KY
27 reviews
Beauty Junkie Expert Level 1
I have tried using this products multiple times over the past couple weeks and it doesn’t do anything for my acne spots, it doesn’t reduce the look of my pimples, clear up my acne spots, nothing. I wish this product worked but it doesn’t. It’s a waist of your money.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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