Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #9 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,791 Q&A

  • Does this product work?3 Answers
  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (11,449)
Q&A (520)
Media (126)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Danielle B.
Mayfield, KY
11 reviews
I struggle with acne and I picked this up to try it out it helped a little but not enough for me to buy it again I think there is better things out there to help out with acne.
Edeline S.
New York, NY
56 reviews
Beauty Junkie Expert Level 1
Whenever I have a pimple or beginning to notice one on my face, all I do is apply a small amount on it and it dries it up and makes it go away faster! Really affordable because a little goes a long way!
Faith C.
19 reviews
This product is a little inconsistent to me. Sometimes I feel I put it on before bed and wake up clear, other times I feel I wasted my time putting it on. It can also be a little bit drying on the skin.
Danny H.
7 reviews
i use it up super quickly. i see improvement on my face super quick. it makes my skin look fresh and healthy. it removes the stubborn pimples and after using it, it disappears.
Katheryn H.
110 reviews
Beauty Junkie Expert Level 4
I’ve used this product a few times, and it seems to help for a while but then eventually it dries my skin out after a few times of using it. It’s priced ok, but the bottle is small. I would like to see it come in a little bigger bottle.
Vivian S.
Palm Bch Gdns, FL
34 reviews
Beauty Junkie Expert Level 1
Hated this. I put it on a breakout I had, not only did it not get rid of it but it dried it out as it was so it wouldn’t go away, and eventually it just left a mark on my face.
isabel c.
8 reviews
Purchased at: Walgreens
love this really good spot treatment and really cheap good value and gets rid of pimple fast this is a little harsh just make sure to have a good moisturizer this has nice packaging i recommend to other
Ingrid L.
West Covina, CA
25 reviews
Beauty Junkie Expert Level 1
Purchased at: Walmart
This stuff really minimizes my acne. I used to poke at them but now I don’t even touch my pimples at all because of this stuff. It gets rid of them in about a week for me since I do have stubborn acne.
Kristi B.
187 reviews
Beauty Junkie Expert Level 4
I felt like this did its job of helping to get rid of pimples. I’d put this on at night, a nice big dollop, and the next day there would be a big difference in my pimple so that it helped it going away faster!
Alicia C.
San Antonio, TX
47 reviews
Beauty Junkie Expert Level 1
Purchased at: ULTA
I love this so much. Every time I get a pimple or a see one coming out, I always dab a little bit and it makes it less noticeable. It does speed up the process of removing it, I recommend this product!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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