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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,308 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10308)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Desiree L.
233 reviews
Beauty Junkie Expert Level 3
*Just an FYI i have overall clear skin* My friend was the first one to tell me about this product. Because i rarely have breakouts I just never tried it thinking "it is not the right product for my needs" Well one month, out of nowhere, my face was struck with acne by my chin and jawline. I was horrified considering the next day I had a Christmas party to attend. I decided to give this stuff a try. I washed my face thoroughly and applied this spot treatment everywhere there was a pimple. I wasn't very hopeful. I woke up the next morning dreading looking at my face and to my surprise THEY WERE GONE. Like literally dried up and vanished. I had to call my friend right away. For $5/$6 if you need a blemish gone GET THIS HOLY GRAIL PRODUCT!
Ally S.
20 reviews
Works great! Got rid of my acne the next day! It did exactly what I needed it to do without breaking the bank! Will definitely purchase again. Very gentle on my skin!
Becca S.
Louisville, KY
32 reviews
Beauty Junkie Expert Level 1
I like this product, but it’s not a favorite.
It does diminish blemishes, but not as quickly as other spot treatments I’ve used.
It also doesn’t wear the best underneath of makeup, it leave a film on the skin.
Abbey R.
13 reviews
I didn’t think this was as effective as I’ve heard it is. To be fair, I have stubborn acne. If you get occasional pimples, it might work better for you. I most likely wouldn’t repurchase.
Priscila P.
18 reviews
I love, I use whenever a spine has arisen and on a dry day it all, and on the second day it does not even look like the spine, in the third it just disappeared.
Used to use a lot as a teen, works better than putting nothing on. I have found other products that work better for my skin. The pro to this is that in a pinch you can find in anywhere, both target and Walmart sell it.
Natassia F.
15 reviews
The smell is not so great. It does burn a little especially on open skin but it works amazingly. Can definitely see a difference by the following day. If not a few hours later depending on the size of the breakout.
Rachael C.
56 reviews
Works very well as a spot treatment. My kids are currently using this. Anytime the face a blemish they put this on and it's cleared up much faster than on its own
Brooke B.
23 reviews
Beauty Junkie Expert Level 1
I honestly don’t feel like this product helped my acne at all. It has nice packaging. It is definitely pricey for the amount you get. I don’t recommend to others.
Vel D.
87 reviews
Beauty Junkie Expert Level 4
Omg! I can't say enough good things about this product...it works! I used to have bad acne but over the years it changed to occasional breakouts, but what I suffer the most of is those little annoying under the skin bumps. Not only does this product dry out my pimples within ONE day, but it has also helped diminish does tiny bumps and the texture of my skin is getting better day by day. I've tried many acne products, especially the expensive ones and nothing has worked like this. Highly recommend it!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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