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Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars47%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,266 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

see more...

Top Questions See all 1,687 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10266)
Q&A (463)
Media (121)
  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big zit..it sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Alina M.
Port St Lucie, FL
108 reviews
Beauty Junkie Expert Level 3
It's my favorite acne spot treatment. It dries out the pimple and reduces the size and redness of the pimple. It doesn't smell the best but it does the job amazingly.
Kenia A.
Santa Ana , CA
136 reviews
I love this spot treatment product from clean and cleari didn’t think it would actually work by it did! You can put it on your pimples before bed and they will be gone the next morning it is amazing!
I loved this product! I put it on at night and in the morning my acne already looked better! It was very effective. I would highly recommend to anybody. It was smooth and soft on my skin. This is a great product.
Darian P.
Rapid City
16 reviews
This works fast! I can put it on a zit or two and in a couple of hours I can see a noticeable change! It can make the pimples a bit redder, so be careful of that.
Tyleen S.
60 reviews
Beauty Junkie Expert Level 1
It gets rid of those pesky pimples overnight! I’ve definitely had days wear skin care just isn’t working for those persistent spots, and use this to fix it quick!
Eva E.
11 reviews
I love this product. It is the only spot treatment that works for me and it immediately makes a difference. I prefer this over any others, such as proactiv. And it has never been too harsh. I put this on at night and the next day the pimple is gone
Kelly E.
48 reviews
Beauty Junkie Expert Level 1
I use this on my troublesome spots. It works super well, but my skin is so sensitive that if I use it too much it tends to dry my skin out and it becomes kind of flaky and gross. Other than that, it’s great.
RobinandBrandi M.
404 reviews
Beauty Junkie Expert Level 5
Helps but wish I could say it works instantly. In the same time it takes normally for a zit to disappear is when I notice a slight disappearance so it's a toss up
Ariana N.
10 reviews
works well but not skin sensitive. it can be painful depending on the acne type. it also can cause whitening of cream as it dries if too much is applied. it does not aid in scarring.
Kaylee M.
6 reviews
It's amazing for people who only have acne in a few spots. I use it at night in my problem areas (usually my forehead) and they're gone by the time I wake up 10/10 would recommend!!!
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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