Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,548 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10548)
Q&A (464)
Media (122)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Amber H.
43 reviews
Beauty Junkie Expert Level 1
Clears up a pesky zit over night. Reduces redness and swelling. A great spot treatment. Would not recommend applying all over the face at once or applying close to eyes. Good product and not too expensive.
Nancy H.
Coloroado springs
95 reviews
Beauty Junkie Expert Level 1
Purchased at: Macy's
This is great for whenever you have a blemish that you need to get rid of super fast. It doesn’t dry out your face like a lot of face washes and you can use it sparingly or all over if needed.
Lesley A.
baroda, mi
131 reviews
I personally love this. It’s easy to apply, easy to carry around in a small bag inside your purse. I usually see results on 1-2 days. A little harsh on the dryness but it could be just my skin.
Michelle V.
Portage, MI
84 reviews
Beauty Junkie Expert Level 3
This works great to just put on my pimples and not have to rub it all over and it almost has them gone by morning, and it’s pretty gentle not harsh like other spot treatments
Samantha F.
Lodi, OH
42 reviews
Beauty Junkie Expert Level 2
I love this spot treatment! This has been so helpful when there is a pesky pimple that pops up and you need a quick solution! Would use again and would recommend to anyone.
Jana R.
La Porte, TX
55 reviews
Beauty Junkie Expert Level 2
My go to when I feel a pimple coming on. It’s clear and easy to apply. It reduces the size of the pimple most of the time overnight. I only get occasional pimples so one tube will last me a long time!
Katherine N.
Manteca, CA
61 reviews
Beauty Junkie Expert Level 2
This helped me for the most part on treating my pimples. But sometimes after putting on the products I would get itchy in that spot for a while until the sensation goes away.
Emily L.
Daytona Beach, FL
98 reviews
Beauty Junkie Expert Level 4
This really helped clear my pimples, I did find it drying but that is expected. I could only use a little bit because I have sensitive skin but overall really great. 
Rebecca N.
Saline, MI
26 reviews
Beauty Junkie Expert Level 1
My go-to for any problem spots that I might have! It’s soft on the skin and it’s so effective in reducing redness at the area! I love this stuff and will continue to use it for any problem areas!!
charlotte w.
united states
54 reviews
Beauty Junkie Expert Level 1
Purchased at: Walmart
I started 2 use this product when it first came out. It's now a staple for me. For those who are considering getting this to treat their everyday acne, this is not the product for you.
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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