Clean & Clear® Advantage® Acne Spot Treatment

BY CLEAN & CLEAR #4 in Acne Treatments

4.0 out of 5 stars
  • 5 Stars46%
  • 4 Stars28%
  • 3 Stars15%
  • 2 Stars6%
  • 1 Star4%
4.05 / 5 based on 10,530 Reviews


  • The second you put it on, the powerful gel with breakthrough technology starts to dissolve surface oil on the skin.
  • With oil out of the way the clinically proven acne medicine can then penetrate pores.
  • The medication starts to clear pimples immediately, with maximum strength 2% Salicylic acid.
  • Pimples are reduced in size, swelling and redness, and the formula won’t over-dry your skin.
  • Voila! Pimple looks better. Now get out there and have some fun!

Recomended for:

Skin Need: Oil, Pimples


  • Because this is a medicine, it’s super important to start with clean skin.
  • So wash your face then apply a thin layer over your face. You can do this up to 3 times a day.
  • If your skin starts to dry out or peel, reduce your use to once a day. 


Salicylic Acid (2%)
Water SD Alcohol 40-B Hamamelis Virginiana (Witch Hazel) Water Polyacrylamide Glycerin C13-14 Isoparaffin Cyclopentasiloxane C12-15 Alkyl Lactate Alcohol Laureth-7 Phenoxyethanol Cetyl Lactate PPG-2 Isoceteth-20 Acetate Cocamidopropyl PG-Dimonium Chloride Phosphate Polysorbate 20 Phenethyl Dimethicone Fragrance Dehydroxanthan Gum Propylene Glycol Benzalkonium Chloride Ammonium Hydroxide Tetrasodium EDTA Butylene Glycol Capryloyl Glycine Sarcosine Cinnamomum Zeylanicum Bark Extract Cedrus Atlantica Bark Extract Portulaca Oleracea Extract


For external use only.
When using this product
- Skin irritation and dryness is more likely to occur if you use another topical acne medication at the same time. If irritation occurs, only use one topical acne medication at a time.
- Rinse right away with water if it gets in eyes

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Top Questions See all 1,688 Q&A

  • Does this really works? my face is breaking out and I wan...1 Answers
  • Is this really helpful to people acne's or just not good ...4 Answers
  • Has anyone tried this?? Is it effective?7 Answers
Clean & Clear® Advantage® Acne Spot Treatment
Clean & Clear® Advantage® Acne Spot Treatment
Reviews (10530)
Q&A (464)
Media (121)
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  • "honestly i like this prodcut and it does help get rid of pimpples but it peels your skin and leaves the area very dry and if i put makeup over it it just looks ugly but it does what it says it would" in 51 reviews
  • "this worked wonders for me but i found after a while of using it stopped working for me?im not sure if i used it too much that my skin got used to it or what but it works great it didnt dry out my skin or anything and it did what it claimed to do!" in 47 reviews
  • "I used these clean and clear product when i have a big sting when applying but the next day is gone leaving a acne mark." in 40 reviews
  • "I put some of this on after my moisturizer at night and by morning the swelling has gone down and if i reapply the pimple will go away after a day or 2." in 37 reviews
  • "This is a life saver everytime I feel a big prople coming I put this one and boom next morning its gone its soo good and cheap" in 24 reviews
Gabby A.
Cumming, GA
73 reviews
Beauty Junkie Expert Level 2
This is my favorite spot treatment ever, I have been using it since middle school. It works and isn’t too drying. I recommend using at night and sometimes morning, because it works under makeup still.
Bre C.
Virginia Bch, VA
23 reviews
Beauty Junkie Expert Level 1
I absolutely love this spot treatment. I used this product a couple of days before my wedding and the pimple I applied it to were no where to be found in my wedding pictures.
Darling A.
Chino , CA
7 reviews
Purchased at: Walgreens
This product has cleared up the few pimples I have here and there. I would recommend it’s nice on skin but tough against acne. I love this product and will continue to use it
Karissa B.
Saint Marys, GA
72 reviews
Beauty Junkie Expert Level 2
This spot treatment is my ride or die. It dries out my breakouts without making the area all weird and dry. I’ve been purchasing and using this spot treatment since I was 16!
Pinal P.
Fayetteville, AR
188 reviews
Beauty Junkie Expert Level 3
This is definitely a lifesaver for surprise acne. I usually apply this once every morning (twice a day if there are super bad spots) and by day two, there’s hardly anything there. Just remember to spread this thin over the area, otherwise, it’ll start flaking once dried and then it just looks super weird on your face. This is nice for the price, though, and clears up a spot within a few days. 
Tallulah P.
28 reviews
Beauty Junkie Expert Level 1
I liked this product. I definitely saw a difference in my blemish when I put this on, however it wasn’t the difference that I wanted. The product was a strong chemical smell and melts of the face when it rains. I have not repurchased.
Kareli S.
Pahrump, NV
70 reviews
Beauty Junkie Expert Level 2
Makes those pesky blemishes disappear in a flash!! I like it a lot and actually need to get a new tube!... Probably will vo to the store tomorro I just can't get enough of it
Madelyn G.
Conway, AR
70 reviews
Beauty Junkie Expert Level 1
I️ love this product. I️t takes of layers of dead skin and opens pores. I️t seems to do a lot even when using little product. Plus, I️t smells like red wine, and I️ like that
Caitlin K.
111 reviews
Beauty Junkie Expert Level 2
My favorite spot treatment I've been using for years and years. Is pretty strong and can burn on more open type acne. But it does the job so well. Well worth the cheap price.
B e.
53 reviews
Beauty Junkie Expert Level 1
Its great i cannot stress it enough! As long as you are used to the burning sensation (which proves its working) the results are absolutely worth it! I use it every other day and have combination skin
Cheryl T.
Gulf Shores, AL
73 reviews
Did anyone experience dryness with this product?
Jana M.
Andover, CT
60 reviews
I know you can use this as a spot treatment and just dab it on the pimples, but can you put a thin layer all over your face to prevent new ones from appearing?
Marie T.
Houston, TX
232 reviews
Beauty Junkie Expert Level 5
Is it worth the money since they're small?
Mackenzie C.
Holbrook, MA
101 reviews
Beauty Junkie Expert Level 4
Does this burn?
Blanca C.
182 reviews
Beauty Junkie Expert Level 5
Did it dry out anyone elses face where you applied it? I'm not a fan of this

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