Yes, you would take the inserts out (if there are any) and throw everything in the washing machine. I use the setting that will put the most water in the washer. Having lots of water is one of the most important things to getting diapers clean. I prefer Charlie's Soap, but there are many cloth diaper safe detergents, including All Free and Clear. Wash on the longest cycle on the highest soil setting. I prefer to use hot water. Then Rinse twice. Line dry the covers for the best lifespan of the covers, you can dry the inserts.