Benz-O-Sthetic Oral Pain Relief Gel Treats Mouth And Gum Irritations It is an oral analgesic gel used for the temporary relief of pain due to minor irritation or injury of the mouth and gums. It contains the active ingredient benzocaine (20 percent), which is a safe and effective ingredient for the temporary relief of pain due to minor irritation of the mouth and gums caused by dentures or orthodontic appliances or associated with canker sores. Treating pain from mouth and gum irritations (eg, canker sores). It may also be used for other conditions as determined by your doctor. Benz-O-Sthetic gel in a local anesthetic. It works by numbing sensitive and painful areas.