This product is doctor recommended to provide immediate cooling, soothing relief from the discomfort associated with migraine, headache, fever, muscle aches, sprains, over-exertion, hot flashes or whenever you need relief. It provides immediate cooling relief in a convenient disposable product. It needs no refrigeration and is portable. Ready to use anywhere and anytime at home, at work or while traveling. For adults. Gently adheres to your skin. Offers just the right amount of cooling to maximize comfort. Cooling effect of each sheet last up to 8 hours. Non-medicated, safe to use with medications. 6 sheets - 2® x 5-1/8®.