Oxymetazoline HCl - Nasal Decongestant Won t drip from nose or down throat. Fast, Powerful Congestion Relief Afrin - Number One Brand in Doctor and Pharmacist Recommendations Afrin No Drip is a breakthrough in nasal sprays. It stays where you spray it without messy dripping from your nose or down your throat. It contains a special blend of ingredients that soothes and moisturizes dry irritated nasal passages. It starts to work in seconds, providing 12 hours ofcomfortable nasal congestion relief withno drowsiness.